Evidence map›Paper›PMID 41060779›Full record

ArticleJournal of mass spectrometry : JMS2025

Simplified Analysis of Native Steroid Esters in Dried Blood Spots by LC-MS

Andreas Thomas, Jasmin Thelen, Panagiotis Sakellariou, Mario Thevis

Abstract read
In one paragraph

Article in Journal of mass spectrometry : JMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreas ThomasInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0003-1199-0743
Jasmin ThelenInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.
Panagiotis SakellariouInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.
Mario ThevisInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-1535-6451

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroidal esters (e.g., testosterone, nandrolone and boldenone esters) belong to the substance class prohibited in professional sport that is particularly frequently abused due to its considerable performance-enhancing effects. Thus, a high number of adverse analytical findings in doping controls is reported every year. Unfortunately, the analysis of steroids that are not exclusively of exogenous nature and, in particular, their differentiation from endogenously produced steroids is very time-consuming and resource-intensive (necessitating isotope-ratio mass spectrometric analysis). The direct detection of the applied (unequivocally exogenous) steroidal esters in blood or dried blood spots (DBS) can offer a much simpler approach. In the present project, the analysis of 17 underivatized steroidal esters (composed of testosterone, nandrolone and boldenone species) is reported, employing liquid chromatography-(low-resolution)-MS

Indexed as

Dried Blood Spot TestingEstersSteroidsTandem Mass SpectrometryChromatography, LiquidDoping in SportsHumansLimit of DetectionSubstance Abuse DetectionTestosteroneEstersSteroidsTestosteronedoping controldried blood spotsLC–MS3LC–MS/MStestosterone

Identifiers

PMID41060779
PMCPMC12507138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.