Evidence map›Paper›PMID 41060760›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Guanine storage vacuoles sequester guanine crystals and serve as nitrogen reserves in

Ursula Goodenough, Robyn Roth, Jae-Hyeok Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Control Strategies in Guanine Biocrystallization.Angewandte Chemie (International ed. in English) · 2026
    Review
  3. Article
  4. Crystalline guanine: Rediscovery of a long-overlooked structure of unicellular eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ursula GoodenoughDepartment of Biology, Washington University, St. Louis, MO 63130.ORCID 0000-0002-7924-9858
Robyn RothCenter for Cellular Imaging, Washington University School of Medicine, St. Louis, MO 63112.ORCID 0000-0001-7823-776X
Jae-Hyeok LeeDepartment of Biological Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.

Funding

Canadian Government | NSERC | RES'EAU-WaterNET 418471-12DOE | Office of Energy Efficiency and Renewable Energy (EERE) DE-EE0003046 fromInternational Center for Energy, Environment and Sustainability, Washington University naUniversity of Manitoba internal funds 325895U.S. Department of Energy (DOE) DE-SC0006873
6 · The paper itself

Abstract

Nitrogen cycles in

Indexed as

Chlamydomonas reinhardtiiGuanineNitrogenVacuolesCrystallizationGuanineNitrogenacidocalcisomesChlamydomonasguanine crystalsmicroalgaenitrogen cycle

Identifiers

PMID41060760
PMCPMC12541418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.