Evidence map›Paper›PMID 41060750›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Functional genetic elements of a butterfly mimicry supergene.

Nicholas W VanKuren, Sofia I Sheikh, Claire L Fu, Darli Massardo, Namiko N Service, Wei Lu, Marcus R Kronforst

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Nicholas W VanKurenDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.ORCID 0000-0001-8633-8851
Sofia I SheikhDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.ORCID 0000-0002-0991-8913
Claire L FuDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.ORCID 0009-0007-5901-107X
Darli MassardoDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.ORCID 0000-0003-2538-1025
Namiko N ServiceDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.ORCID 0009-0001-6485-4369
Wei LuDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.
Marcus R KronforstDepartment of Ecology & Evolution, The University of Chicago, Chicago 60637, IL.ORCID 0000-0002-9825-891X

Funding

Characterizing the Molecular Basis of Supergene Mimicry in ButterfliesR35GM131828 · NIGMS · UNIVERSITY OF CHICAGO · PI Marcus Kronforst · 2019 to 2026
$3.3M
HHS | National Institutes of Health (NIH) GM131828NIGMS NIH HHS R35 GM131828
6 · The paper itself

Abstract

Development requires the coordinated action of many genes across space and time, yet numerous species can develop discrete, alternate phenotypes. Such complex balanced polymorphisms are often controlled by supergenes: multiple tightly linked loci that function together to control development of a complex phenotype. Supergenes are widespread in nature. However, the evolution and functions of supergene alleles remain obscure because the identities of the functional loci, and the causative variation between them, remain essentially unknown. The

Indexed as

Biological MimicryButterfliesGenes, InsectAllelesAnimalsEvolution, MolecularInsect ProteinsPhenotypePigmentationWings, AnimalInsect Proteinsautoregulationco-optionepistasispolymorphismsexual dimorphism

Identifiers

PMID41060750
PMCPMC12541413

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.