Evidence map›Paper›PMID 41060600›Full record

ArticleAnnals of surgical oncology2025

Implementation of an Enhanced Recovery After Surgery Pathway for Pediatric Surgical Oncology using Quality Improvement Methodology.

Shachi Srivatsa, Jennifer H Aldrink, Elizabeth Schneider, Taha Akbar, Giorgio Veneziano, Vanessa Ng, Cindy McManaway, Dana Schwartz, Kris Jatana, Sara A Mansfield

Abstract read
In one paragraph

Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shachi SrivatsaCenter for Surgical Outcomes Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Jennifer H AldrinkDivision of Pediatric Surgery, Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
Elizabeth SchneiderCenter for Clinical Excellence, Nationwide Children's Hospital, Columbus, OH, USA.
Taha AkbarCenter for Surgical Outcomes Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.
Giorgio VenezianoDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
Vanessa NgDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
Cindy McManawayDivision of Pediatric Surgery, Department of Surgery, Nationwide Childrens Hospital, Columbus, OH, USA.
Dana SchwartzDivision of Pediatric Surgery, Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
Kris JatanaDepartment of Otolaryngology, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA.
Sara A MansfieldDivision of Pediatric Surgery, Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA. Sara.mansfield@nationwidechildrens.org.ORCID http://orcid.org/0000-0002-2868-0947

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced recovery after surgery (ERAS) pathways have demonstrated significant benefits, but often face challenges in implementation due to the scope of process measures and multidisciplinary buy-in required. This study aimed to standardize surgical care for children undergoing solid tumor resection by implementing an ERAS for Tumor (ERAST) pathway. PATIENTS AND

methodsOur ERAST pathway consisted of 20 process measures. Plan-Do-Study-Act (PDSA) cycles were utilized, including implementing standardized pre- and postoperative orders, data-enabled electronic progress note templates, and multidisciplinary preoperative team huddles. Our primary outcome was 80% adherence to protocol process measures. Secondary outcomes included hospital length-of-stay (LOS) and opioid usage. Balancing measures included readmission and/or emergency room visits within 30 days post-procedure.

resultsOver 15 months, 57 patients (63 surgeries) were included. Median adherence to process measures was 89.5%. Intraoperative fluid administration decreased from 12.19 to 5.97 ml/kg/h (p < 0.001). Intraoperative opioid use in abdominal cases fell from 0.37 to 0.24 OME/kg (p = 0.0008); postoperative opioid use dropped from 0.16 to 0.04 OME/kg/day (p < 0.001). Thoracic cases saw post-operative opioid use decrease from 0.30 to 0.13 OME/kg/day (p = 0.0017). Median LOS decreased for laparotomy (4.48-2.87 days), thoracotomy (3.37-2.26 days), and thoracoscopy (1.60-1.15 days), all p < 0.001. There was no difference in readmission and/or emergency room visits pre/post ERAST for all cases.

conclusionsThe ERAST pathway achieved high protocol adherence and led to significant reductions in opioid use and LOS, without worsening balancing measures. This demonstrates the effectiveness of multidisciplinary, protocol-driven recovery pathways in pediatric surgical oncology.

Indexed as

Critical PathwaysEnhanced Recovery After SurgeryNeoplasmsQuality ImprovementSurgical OncologyAdolescentAnalgesics, OpioidChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantLength of StayMalePatient ReadmissionAnalgesics, OpioidERASPediatric surgical oncologyRegional anesthesia

Identifiers

PMID41060600
PMCPMC12589384

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.