ArticleApplied biochemistry and biotechnology2025
Xylonic Acid Production from Sugarcane Bagasse Hydrolysate Using an Engineered Komagataella phaffii Strain.
Article in Applied biochemistry and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Xylonic acid is an oxidized derivative of xylose that is used by the food, pharmaceutical, and chemical industries. It can be produced either microbially or chemically. Biological production is advantageous because of its safety, eco-friendliness, and mild process conditions. This study used a recombinant Komagataella phaffii strain modified to produce xylonic acid from xylose. Glucose and glycerol were evaluated as co-substrates in batch and fed-batch fermentations in flasks and in bioreactor cultures. Glycerol was an effective carbon source for improving growth and product production. Batch fermentations with glycerol produced 24.88 ± 1.64 g.L
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