Evidence map›Paper›PMID 41060516›Full record

ArticleEuropean radiology experimental2025

Advanced diffusion-relaxation imaging for tumoral differentiation and metastasis prediction in oral tongue cancer.

Siyu Li, Wentao Hu, Gongxin Yang, Xiaofeng Zheng, Yifeng Huang, Dongmei Wu, Yingwei Wu, Yongming Dai

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Article in European radiology experimental, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Siyu Li *Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wentao Hu *Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gongxin YangDepartment of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaofeng ZhengDepartment of Oral Pathology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yifeng HuangDepartment of First Dental Clinic, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Research Institute of Stomatology, Shanghai, China.
Dongmei WuShanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China.
Yingwei WuDepartment of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wuyw0103@hotmail.com.
Yongming DaiSchool of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China. dymdym118@163.com.ORCID http://orcid.org/0000-0002-6084-9685

Funding

Cross Disciplinary Research Fund of Shanghai Ninth People's Hospital No. JYJC202107National Natural Science Foundation of China No. 82373114
6 · The paper itself

Abstract

backgroundTo determine the feasibility of diffusion-relaxation correlation spectroscopic imaging in identifying tumoral differentiation profile and predicting cervical lymph node metastasis (CLNM) in oral tongue squamous cell carcinoma (OTSCC). MATERIALS AND

methodsThis prospective study enrolled fifty-seven OTSCC patients who underwent preoperative head and neck magnetic resonance imaging (MRI). Scans with multi b-values (0-1500 s/mm

resultsThirty-four patients were assigned to the CLNM+ group and 23 to the CLNM- group. CLNM+ patients showed larger tumor maximal diameters, deeper invasion, increased V

conclusionDiffusion-relaxation correlation spectroscopic imaging marked a significant advancement in the diagnostic and prognostic assessment of OTSCC, offering detailed tumor characterization and improving CLNM+ prediction, with great potential for accurate and non-invasive evaluation. RELEVANCE STATEMENT: Diffusion-relaxation correlation spectroscopic imaging metrics (V KEY POINTS: Tumoral components and heterogeneity of oral tongue cancer were investigated on MRI. Advanced diffusion-relaxation imaging delineated the tumoral differential profile and predicted metastasis. We provided a non-invasive tool for preoperative decision-making in clinical workflows.

Indexed as

Carcinoma, Squamous CellDiffusion Magnetic Resonance ImagingTongue NeoplasmsAdultAgedFemaleHumansLymphatic MetastasisMaleMiddle AgedProspective StudiesCarcinoma (squamous cell)Diffusion magnetic resonance imagingNeoplasm metastasisPerineural invasionTongue neoplasms

Identifiers

PMID41060516
PMCPMC12508348

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