Evidence map›Paper›PMID 41060461›Full record

ArticleEuropean journal of applied physiology2026

No sex differences in fat oxidation in response to exercise prescribed according to maximal heart rate or ventilatory threshold.

Todd A Astorino, Alex J MacDonald, Alex Anderson, Hanna Lauritzen, Ryan Pinter, Hailey Schepper, Dalton Ferguson

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Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Todd A AstorinoDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA. astorino@csusm.edu.ORCID http://orcid.org/0000-0003-0492-0173
Alex J MacDonaldDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA.
Alex AndersonDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA.
Hanna LauritzenDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA.
Ryan PinterDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA.
Hailey SchepperDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA.
Dalton FergusonDepartment of Kinesiology, California State University-San Marcos, 333. S. Twin Oaks Valley Road, UNIV 320, San Marcos, CA, 92096-0001, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimMost data report that women exhibit higher fat oxidation (FOx) than men during exercise, yet studies typically prescribe exercise using percent maximal heart rate or oxygen uptake (%HR/VO PURPOSE: To examine sex differences in substrate metabolism when exercise is prescribed using %HRmax and ventilatory threshold (VT).

methodsActive men (n = 24) and women (n = 25) underwent incremental cycling to determine VO

resultsAt 62%HRmax (workload = 31 ± 6 vs. 24 ± 7%PPO, p < 0.001), there was no difference in RER (0.88 ± 0.05 vs. 0.85 ± 0.06, p = 0.12) or FOx (4.6 ± 2.3 vs. 4.8 ± 2.0 mg/kg FFM/min, p = 0.78) between men and women, although men revealed higher carbohydrate oxidation (CHOOx) versus women (16.4 ± 4.8 vs. 12.9 ± 6.1 mg/kg FFM/min, p = 0.03). Cycling at 30% below VT (workload = 46 ± 5 vs. 44 ± 7%PPO, p = 0.20) revealed no difference in RER (0.92 ± 0.06 vs. 0.90 ± 0.05, p = 0.16), FOx (3.9 ± 3.2 vs. 4.8 ± 2.6 mg/kg FFM/min, p = 0.49), or CHOOx (27.3 ± 7.8 vs. 24.6 ± 11.1 mg/kg FFM/min, p = 0.35).

conclusionData reveal no sex differences in FOx when exercise is prescribed according to VT or %HRmax.

Indexed as

ExerciseHeart RateLipid MetabolismAdultFemaleHumansMaleOxidation-ReductionOxygen ConsumptionSex CharacteristicsSex FactorsYoung AdultBlood lactate concentrationCyclingFat utilizationRespiratory exchange ratioSubstrate metabolism

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.