Evidence map›Paper›PMID 41060388›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Network pharmacology, molecular docking, molecular dynamics simulation, and in vivo experiments elucidate the potential mechanisms of berberine against liver injury.

Lun Zhang, Lijuan Cheng, Qianqian Huang, Yun Yu

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lun Zhang *Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Lijuan Cheng *Department of Pharmacy, Anhui No.2 Provincial People's Hospital, Hefei, 230012, China.
Qianqian HuangDepartment of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China. 1138446546@qq.com.
Yun YuDepartment of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China. 15056920257@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Berberine (BBR), a compound extracted from Coptis chinensis Franch, has been used in traditional Chinese medicine to treat liver diseases due to its anti-inflammatory, antioxidant, and liver-protective properties. To explore its therapeutic effects and underlying mechanisms in CCl

Indexed as

Anti-Inflammatory AgentsBerberineChemical and Drug Induced Liver InjuryAnimalsCarbon TetrachlorideDisease Models, AnimalLiverMaleMiceMice, Inbred C57BLMolecular Docking SimulationMolecular Dynamics SimulationNetwork PharmacologySignal TransductionAnti-Inflammatory AgentsBerberineCarbon TetrachlorideBerberineLiver injuryMolecular dynamics simulationMolecular mechanismNetwork pharmacology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.