ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2025
Biomineralized gold nanoparticle-based colorimetric sensing platform for ascorbic acid detection.
Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Beyond ensemble averages: single-entity approaches for complex systems.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Review
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7 authors.
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Abstract
Ascorbic acid (AA), a critical regulator of redox homeostasis, plays a vital role in disease prevention. Thus, the development of a rapid and precise detection method is urgently needed. In this work, a colorimetric sensing platform based on bioinspired mineralization-synthesized gold nanoparticles (AuNPs) was proposed for the visual and rapid detection of AA. The as-prepared AuNPs exhibited uniform morphology and excellent oxidase-like activity, efficiently catalyzing 3,3',5,5'-tetramethylbenzidine (TMB) oxidation to produce a characteristic 650 nm absorption peak. However, in the presence of AA, TMB oxidation was significantly inhibited due to the reducing property of AA. The color change was visually detectable within 5 min. The absorbance at 650 nm linearly decreased with the AA concentration in the range of 1-60 μM (R
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