Evidence map›Paper›PMID 41060371›Full record

ArticlePediatric dermatology

Successful Treatment of Severe Purpura Fulminans With Anakinra.

Francesco Zulian, Luca Spiezia, Antonio Amabile, Francesca Tirelli, Alessandra Meneghel

Abstract readCase Reports
In one paragraph

Article in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesco ZulianDepartment of Women's and Children's Health, Padova University Hospital, Padova, Italy.ORCID https://orcid.org/0000-0002-2479-3485
Luca SpieziaDepartment of Medicine, Padova University Hospital, Padova, Italy.ORCID https://orcid.org/0000-0003-4339-8525
Antonio AmabileClinic of Plastic Surgery, University Hospital of Padua, Padova, Italy.ORCID https://orcid.org/0009-0005-4286-1006
Francesca TirelliDepartment of Women's and Children's Health, Padova University Hospital, Padova, Italy.ORCID https://orcid.org/0000-0002-9947-4059
Alessandra MeneghelDepartment of Women's and Children's Health, Padova University Hospital, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities. The management of PF requires a comprehensive approach, including the treatment of the underlying infection, anticoagulation, and anti-inflammatory therapy. Herein we present the case of a child with severe PF successfully treated with anakinra, an anti-IL1-receptor monoclonal antibody.

Indexed as

Interleukin 1 Receptor Antagonist ProteinPurpura FulminansChildFemaleHumansMaleSeverity of Illness IndexTreatment OutcomeInterleukin 1 Receptor Antagonist Proteinbiological agentdisseminated intravascular coagulation (DIC)skin necrosistherapy

Identifiers

PMID41060371
PMCPMC13051000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.