Evidence map›Paper›PMID 41060091›Full record

ArticleJournal of bacteriology2025

Inhibitory proteins of

Saikat Mandal, Alanah Soriano, Caroline Erpelding, Jackson Ruffner, Eric Smith, Benjamin J Orlando, Lee Kroos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saikat Mandal *Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0002-2854-1015
Alanah Soriano *Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.
Caroline Erpelding *Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.
Jackson Ruffner *Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.
Eric Smith *Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.
Benjamin J OrlandoDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0001-7079-8140
Lee KroosDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0002-4294-948X

Funding

SWITCH GOVERNING BACILLUS MOTHER CELL GENE EXPRESSIONR01GM043585 · NIGMS · MICHIGAN STATE UNIVERSITY · PI KROOS, LEE R · 1995 to 2021
$4.8M
Structural Basis of Antimicrobial Peptide Sensing and ResistanceR35GM146721 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Benjamin Joseph Orlando · 2022 to 2026
$1.9M
Michigan State University AgBioResearch MICL02710NIGMS NIH HHS R01 GM043585NIGMS NIH HHS R35 GM146721NIH HHS R01 GM43585NIH HHS R35 GM146721
6 · The paper itself

Abstract

Intramembrane proteases (IPs) are crucial for diverse signaling pathways, including some that regulate the virulence of pathogenic bacteria. A better understanding of mechanisms controlling IP activity is necessary to guide therapeutic development.

Indexed as

Bacillus subtilisBacterial ProteinsCell MembraneMembrane ProteinsPeptide HydrolasesEscherichia coliGene Expression Regulation, BacterialProtein BindingBacterial ProteinsMembrane ProteinsPeptide HydrolasesBacillus subtilisBofAintramembrane proteaseregulated intramembrane proteolysisSpoIVFASpoIVFBsporulation

Identifiers

PMID41060091
PMCPMC12632252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.