Evidence map›Paper›PMID 41060038›Full record

Trial reportPsychophysiology2025

Effects of Olfactory Learning Context Reactivation During Sleep on Training Success in a Double-Blind Randomized Controlled Sensorimotor Rhythm Neurofeedback Protocol: A Pilot Study.

Julia Lechinger, Catarina Newe, Svenja Nadler, Marlene Schubert, Hong-Viet V Ngo, Robert Göder, Alexander Prehn-Kristensen

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia LechingerCentre for Integrative Psychiatry, University Hospital Schleswig-Holstein, Kiel, Germany.ORCID 0000-0002-6325-1988
Catarina NeweCentre for Integrative Psychiatry, University Hospital Schleswig-Holstein, Kiel, Germany.
Svenja NadlerInstitute of Child and Adolescent Psychiatry, Centre for Integrative Psychiatry, University Hospital Schleswig-Holstein, Kiel, Germany.
Marlene SchubertCentre for Integrative Psychiatry, University Hospital Schleswig-Holstein, Kiel, Germany.
Hong-Viet V NgoDepartment of Psychology, University of Essex, Colchester, UK.
Robert GöderCentre for Integrative Psychiatry, University Hospital Schleswig-Holstein, Kiel, Germany.
Alexander Prehn-KristensenInstitute of Child and Adolescent Psychiatry, Centre for Integrative Psychiatry, University Hospital Schleswig-Holstein, Kiel, Germany.

Funding

Deutsche Forschungsgemeinschaft 468645090
6 · The paper itself

Abstract

Neurofeedback training (NFT) is used to modulate brain activity for therapeutic purposes in different patient populations. However, tested training protocols vary in several aspects, and the results of therapeutic benefit have been heterogeneous. The aim of the current study was to compare a SMR against a random frequency protocol and potentially strengthen NFT effects via olfactory context reactivation during sleep in a compact training protocol. 49 participants (mean age: 24.7 years; 29 women) without any neurological or psychiatric disorder were randomly (double-blind) assigned to three groups: sensorimotor rhythm (SMR) with or without context reactivation, or random frequencies with reactivation during sleep. Within 2 weeks, participants underwent eight training sessions (12 × 2 min training intervals) and slept three nights in the sleep lab. NFT sessions were scheduled every day or every other day for practical reasons. Nights two and three were used for reactivation. SMR training success was assessed at baseline, post treatment, and follow-up after 10 months. Neurofeedback was provided as pixelated video, which became clearer with better training performance. Although SMR amplitude did not significantly increase, NFT training seemed to have an effect on alpha amplitude over the course of training (p = 0.08), and both SMR groups showed by tendency improved objective sleep (e.g., higher sleep efficiency in night 2 vs. baseline night, p

Indexed as

Brain WavesLearningNeurofeedbackSensorimotor CortexSleepSmellAdultDouble-Blind MethodElectroencephalographyFemaleHumansMalePilot ProjectsYoung Adultalpha frequencycue‐dependent memory reactivationdeclarative memoryneurofeedback trainingpolysomnographysleep spindles

Identifiers

PMID41060038
PMCPMC12506616

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.