Evidence map›Paper›PMID 41060012›Full record

ArticleMicrobiology spectrum2025

Bioluminescent reporter influenza A viruses to track viral infections.

Ramya S Barre, Ahmed Mostafa, Kevin Chiem, Rebecca L Pearl, Roy N Platt, Anastasija Cupic, Timothy J C Anderson, Ulla G Knaus, Randy A Albrecht, Adolfo García-Sastre and 3 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Ramya S BarreTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0002-8773-6349
Ahmed MostafaTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0002-2878-5714
Kevin ChiemTexas Biomedical Research Institute, San Antonio, Texas, USA.
Rebecca L PearlDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Roy N PlattTexas Biomedical Research Institute, San Antonio, Texas, USA.
Anastasija CupicDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Timothy J C AndersonTexas Biomedical Research Institute, San Antonio, Texas, USA.
Ulla G KnausConway Institute, School of Medicine, University College Dublin, Dublin, Ireland.
Randy A AlbrechtDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Adolfo García-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-6551-1827
James J KobieHeersink School of Medicine, Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-8069-0272
Aitor NogalesCenter for Animal Health Research, CISA-INIA-CSIC, Madrid, Spain.ORCID 0000-0002-2424-7900
Luis Martinez-SobridoTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0001-7084-0804

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00014 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GARCIA-SASTRE, ADOLFO · 2021 to 2025
$62.6M
TRAINING PROGRAM: MECHANISMS OF VIRUS-HOST INTERACTIONST32AI007647 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI Domenico Tortorella · 2000 to 2026
$11.5M
Dynamics of the protective vaccine-induced human influenza neuraminidase B cell responseR01AI145332 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KOBIE, JAMES J, MARTINEZ-SOBRIDO, LUIS · 2019 to 2022
$3.0M
American Lung AssociationNational Institute of Allergy and Infectious Diseases 5R01AI145332NIAID NIH HHS 75N93021C00014NIAID NIH HHS R01 AI145332NIAID NIH HHS T32 AI007647Texas Biomedical ForumTexas Biomedical Research Institute
6 · The paper itself

Abstract

Influenza A viruses (IAVs) infect a wide range of mammalian and bird species and are responsible for seasonal outbreaks and occasional pandemics of great consequences in humans. Studying IAVs requires methods to detect the presence of the virus in infected cells or animal models. Recombinant IAV-expressing fluorescent proteins has allowed monitoring of viral infection in cultured cells and

Indexed as

Influenza A virusInfluenza A Virus, H1N1 SubtypeOrthomyxoviridae InfectionsAnimalsAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralAntiviral AgentsDisease Models, AnimalDogsFemaleFerretsGenes, ReporterHumansInfluenza, HumanLuciferasesAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralAntiviral AgentsLuciferasesbioluminescent reporterH1N1in vivo imaging systemsnanoluciferasenon-structural segmentseasonal influenza

Identifiers

PMID41060012
PMCPMC12584733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.