Evidence map›Paper›PMID 41060011›Full record

ArticlemSystems2025

A multi-omics analysis unveils functional and regulatory links between hydroxybenzene and aromatic amino acid metabolism in

Enrico Garbe, Sascha Schäuble, Bettina Böttcher, Robert Jesse, Dominik Driesch, Lasse van Wilijck, Osama Elshafee, Tim Bastian Schille, Bernhard Hube, Gianni Panagiotou and 1 more

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Enrico Garbe *Septomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.ORCID 0009-0007-3435-6637
Sascha Schäuble *Department of Microbiome Dynamics, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.ORCID 0000-0003-3862-6546
Bettina BöttcherSeptomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.
Robert JesseSeptomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.
Dominik DrieschBioControl Jena, Jena, Germany.
Lasse van WilijckInstitut Pasteur, Université Paris Cité, INRAE USC2019, Unité Biologie et Pathogénicité Fongiques, Paris, France.
Osama ElshafeeDepartment Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection BiologyHans Knöll Institute, Jena, Germany.
Tim Bastian SchilleDepartment Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection BiologyHans Knöll Institute, Jena, Germany.
Bernhard HubeDepartment Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection BiologyHans Knöll Institute, Jena, Germany.ORCID 0000-0002-6028-0425
Gianni PanagiotouDepartment of Microbiome Dynamics, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.
Slavena VylkovaSeptomics Research Center, Friedrich Schiller University and Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, Jena, Germany.

Funding

Bundesministerium für Bildung und Forschung 03Z22JN11Deutsche Forschungsgemeinschaft 210879364Deutsche Forschungsgemeinschaft 390713860
6 · The paper itself

Abstract

The fungus IMPORTANCE: The opportunistic human fungal pathogen

Indexed as

Amino Acids, AromaticCandida albicansFungal ProteinsGene Expression Regulation, FungalMetabolic Networks and PathwaysMultiomicsAmino Acids, AromaticFungal Proteins3-oxoadipate pathwayamino acid metabolismCandida albicansgenome-scale metabolic modelingmetabolomicsshikimate pathway

Identifiers

PMID41060011
PMCPMC12625712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.