Evidence map›Paper›PMID 41059835›Full record

Trial reportJournal of the International Society of Sports Nutrition2025

Similar effects between animal-based and plant-based protein blend as complementary dietary protein on muscle adaptations to resistance training: findings from a randomized clinical trial.

Martin Hindermann Santini, Alice Erwig Leitão, Bruna Caruso Mazzolani, Fabiana Infante Smaira, Mariana Silva Camargo de Souza, Andrea Santamaria, Bruno Gualano, Hamilton Roschel

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05710614 (Mixed Plant- vs. Animal-based Supplementary Protein to Support Muscle Adaptations to Resistance Exercise), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05710614 nacompletednot on this map

Mixed Plant- vs. Animal-based Supplementary Protein to Support Muscle Adaptations to Resistance Exercise: a Randomized Clinical Trial

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2023 to 2024Enrolled40ConditionsDietary Supplements, Muscle Strength, Muscle, Skeletal, Resistance TrainingArmsAnimal protein, Plant Protein
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin Hindermann SantiniApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.ORCID 0009-0001-1418-5822
Alice Erwig LeitãoApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.
Bruna Caruso MazzolaniApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.
Fabiana Infante SmairaApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.
Mariana Silva Camargo de SouzaUniversity of Sao Paulo, Center of Lifestyle Medicine, School of Medicine, Sao Paulo, Brazil.
Andrea SantamariaApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.
Bruno GualanoApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.
Hamilton RoschelApplied Physiology and Nutrition Research Group - School of Physical Education and Sport and Faculdade de Medicina FMUSP Universidade de Sao Paulo, Sao Paulo, Brazil.ORCID 0000-0002-9513-6132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent evidence suggests that both animal and plant proteins support strength and hypertrophy gains when paired with resistance training and adequate protein intake. The purpose of this study was to investigate the effects of supplementary protein source (blend of plant-based [PLNT] vs. animal based [ANML]) to habitual diet on changes in muscle mass and strength in healthy young men undertaking resistance training.

methodsForty-four young untrained males were recruited for this study. Subjects were randomly allocated into two groups, and consumed three 15-g daily doses (45 g. d-

resultsBoth groups showed significant (all

conclusionComplementing dietary protein intake with either a blend of plant- or an animal-based protein similarly supported resistance training-induced muscle adaptations.

trial registrationDistinct Sources of Supplementary Protein in the Resistance Exercise Training-induced Adaptations, NCT05710614, 08/01/2023.

Indexed as

Adaptation, PhysiologicalAnimal Proteins, DietaryDietary ProteinsMuscle, SkeletalResistance TrainingAdultDietHumansMaleMuscle StrengthPea ProteinsSoybean ProteinsWhey ProteinsYoung AdultAnimal Proteins, DietaryDietary ProteinsPea ProteinsSoybean ProteinsWhey ProteinsDietary intakemuscle hypertrophyplant-based proteinprotein sourcestrength

Identifiers

PMID41059835
PMCPMC12509290

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.