Evidence map›Paper›PMID 41059669›Full record

ArticleHead & neck2026

Segmental Tracheal Resection for Thyroid Cancer: Perioperative Morbidity, Locoregional Control, and Survival.

Anastasios Maniakas, David C Wilde, Isabelle Fournier, Emily K Hyde, Li Xu, Jennifer R Wang, Neil D Gross, Erich M Sturgis, Victoria Banuchi, Naifa L Busaidy and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Anastasios ManiakasDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-4354-2841
David C WildeDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Isabelle FournierDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Emily K HydeDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0009-0009-5708-8633
Li XuDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jennifer R WangDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-0807-3832
Neil D GrossDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Erich M SturgisDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
Victoria BanuchiDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Naifa L BusaidyDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Maria E CabanillasDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Priyanka IyerDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ramona DaduDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Steven G WaguespackDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-0280-0100
Mimi I HuDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-0355-030X
G Brandon GunnDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michael KwonDepartment of Neuroradiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Salmaan AhmedDepartment of Neuroradiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michelle D WilliamsDepartment of Anatomical Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Mark E ZafereoDepartment of Head & Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-7918-9739

Funding

Eli Lilly and CompanyExelixisJazz PharmaceuticalsMerck
6 · The paper itself

Abstract

backgroundSegmental tracheal resection is rarely needed for advanced thyroid cancer but is among the most complex, high-risk thyroid surgeries.

methodsRetrospective study of patients undergoing segmental tracheal resection for thyroid cancer at MD Anderson Cancer Center (2005-2024).

resultsWe identified 120 patients with a median follow-up of 4.6 years (range 0.02-16.38). Papillary thyroid cancer was most common (68%). The median number of tracheal rings resected was 4 (range 1-9). Seventeen (14%) patients had a new tracheostomy placed at the time of surgery, with 11 (9%) remaining trach-dependent at last follow-up. Twenty-six (22%) patients had a return to the operating room within 30 days, while 3 (3%) patients suffered perioperative mortality. The more common postoperative complications included tracheostomy tube placement (10%), hematoma (7%), and anastomotic air leak (6%). Median hospitalization was 6 days (range 2-67). Locoregional control (LRC) and overall survival (OS) were 79% and 77% at 5 years, respectively.

conclusionsSegmental tracheal resection for advanced thyroid cancer is technically complex and high-risk, but most patients stay recurrence-free 5 years post-surgery.

Indexed as

Thyroid NeoplasmsTracheaAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesThyroidectomyTracheostomyTreatment OutcomeYoung Adultanaplasticfollicularmedullarypapillary thyroid cancerpoorly differentiatedsegmental tracheal resection

Identifiers

PMID41059669
PMCPMC12891758

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.