Evidence map›Paper›PMID 41059629›Full record

ArticleJournal of the International AIDS Society2025

Laser hair removal to antiretrovirals: findings from a person-centred care model for transgender people in India.

Simran Shaikh, Parthasarathy Mugundu Ramien, Jade Bell, Kanchan Pawar, Allison M McFall, Saya Okram, Ajay Enugu, Lakshmi Ganapathi, Maria Salvat Ballester, Viswanathan Arumugam and 9 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Person-centred HIV prevention in an era of innovation and uncertainties.Journal of the International AIDS Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Simran ShaikhThe Johns Hopkins University School of Medicine, New Delhi, India.
Parthasarathy Mugundu RamienThe Johns Hopkins University School of Medicine, New Delhi, India.ORCID https://orcid.org/0000-0001-7498-3896
Jade BellThe Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kanchan PawarThe Johns Hopkins University School of Medicine, New Delhi, India.
Allison M McFallThe Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-1157-2931
Saya OkramY.R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Ajay EnuguThe Johns Hopkins University School of Medicine, New Delhi, India.
Lakshmi GanapathiMassachusetts General Hospital, Boston, Massachusetts, USA.
Maria Salvat BallesterThe Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Viswanathan ArumugamY.R. Gaitonde Centre for AIDS Research and Education, Chennai, India.
Rose Pollard KaptchukThe Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Aditya SinghThe Johns Hopkins University School of Medicine, New Delhi, India.
Shantanu Kumar PurohitNational AIDS Control Organization, New Delhi, India.
Alex KeuroghlianMassachusetts General Hospital, Boston, Massachusetts, USA.
Kevin ArdMassachusetts General Hospital, Boston, Massachusetts, USA.
Shruti H MehtaThe Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Sukhvinder KaurUSAID, New Delhi, India.
Kenneth H MayerHarvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-7460-733X
Sunil Suhas SolomonThe Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-3296-1514

Funding

USAID India Cooperative Agreement 72038619CA00001
6 · The paper itself

Abstract

introductionTransgender women (TGW) in India continue to bear disproportionate HIV burden and face persistent social, legal and structural barriers to receive gender-affirming care.

methodsSince 2021, we established three "Mitr" (meaning: friend) clinics in Hyderabad, Pune and Thane, India, for transgender people with staffing primarily from the community. Mitr clinics provide free HIV testing and pre-exposure prophylaxis (PrEP) on site with linkage to government antiretroviral therapy (ART) centres. They also provide free consultation for gender-affirming hormone therapy (GAHT), subsidized laser hair removal and legal assistance. Client service utilization data were analysed using summary statistics to evaluate uptake of HIV and gender-affirming services; correlates of HIV testing were examined using logistic regression. Semi-structured interviews conducted at one site were used to understand barriers/facilitators of HIV testing.

resultsA total of 5223 unique clients registered between March 2021 and September 2024; median age was 26 years. Most (86%) self-identified as TGW, and 35% reported transactional sex. Most clients (70%) had not previously accessed public sector HIV services. The majority (75%) accessed Mitr clinics for gender-affirming care, including laser hair removal (53%), GAHT consultations (34%) and surgical referral (26%). Over half (62%) of clients eligible for HIV testing underwent screening, of whom 6% were newly diagnosed. Accessing Mitr clinics for gender-affirming surgical services was significantly associated with HIV testing receipt (aOR: 1.51; 95% CI: 1.02, 2.25). Services provided by staff from the community were a prominent facilitator for HIV testing, while stigma and disclosure concerns were notable barriers. Among 585 clients interested in and eligible for PrEP, 576 (98%) initiated PrEP, and 378 (66%) were PrEP persistent at 3 months. Of 454 clients with HIV (newly diagnosed or previously known), 392 (86%) initiated ART. As of 30 September 2024, 233 (59%) were still receiving Mitr clinic services and retained in HIV care; viral suppression was 98% among the 156 clients with data.

conclusionsThe Mitr model highlights the importance of aligning programme and community priorities. The provision of gender-affirming care attracted many clients who might not otherwise have accessed HIV services; indeed, laser hair removal served as the key entry point to HIV testing, PrEP and ART.

Indexed as

Anti-Retroviral AgentsHair RemovalHIV InfectionsTransgender PersonsAdolescentAdultFemaleHumansIndiaMaleMiddle AgedPatient-Centered CarePre-Exposure ProphylaxisYoung AdultAnti-Retroviral Agentscomprehensive servicesgender‐affirming careHIVlow‐ and middle‐income countryperson‐centredtransgender people

Identifiers

PMID41059629
PMCPMC12505023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.