Evidence map›Paper›PMID 41059610›Full record

ArticleTurkish journal of surgery2025

Long-term outcomes of extended versus segmental resection for transverse colon cancer: A population-based analysis based on the SEER database.

Çiğdem Benlice, Metincan Erkaya, Afag Aghayeva, Volkan Özben, Emre Görgün, Deniz Atasoy, Bilgi Baca

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Article in Turkish journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Çiğdem BenliceDepartment of General Surgery, İstanbul Health and Technology University Faculty of Medicine, İstanbul, Türkiye.ORCID 0000-0002-5211-1779
Metincan ErkayaDepartment of Colorectal Surgery, DDSI, Cleveland Clinic, Cleveland, Ohio, US.ORCID 0000-0002-4707-6059
Afag AghayevaClinic of General Surgery, Acıbadem Altunizade Hospital, İstanbul, Türkiye.ORCID 0000-0002-5317-8545
Volkan ÖzbenDepartment of General Surgery, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Türkiye.ORCID 0000-0002-9620-5080
Emre GörgünDepartment of Colorectal Surgery, DDSI, Cleveland Clinic, Cleveland, Ohio, US.ORCID 0000-0001-7725-3522
Deniz AtasoyDepartment of General Surgery, İstanbul Health and Technology University Faculty of Medicine, İstanbul, Türkiye.ORCID 0000-0002-5703-4549
Bilgi BacaDepartment of General Surgery, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Türkiye.ORCID 0000-0003-1704-2533

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate long-term cancer-specific outcomes associated with extended versus segmental colectomy (SC) in patients with stage I-III transverse colon adenocarcinoma using a large, population-based cohort. Material and Methods: Patients who diagnosed with transverse colon cancer undergoing curative-intent colectomy were identified from the surveillance, epidemiology, and end results database (2013-2019). Surgical procedures were categorized as extended colectomy (EC) or SC based on standardized procedural coding. 1:1 propensity score matching was performed to reduce selection bias and balance baseline characteristics. Cancer-specific survival (CSS) was analyzed using multivariable Cox proportional hazards regression. Results: Among 18,799 eligible patients, 58% underwent EC. EC was more frequently performed in individuals with higher tumor stage (p<0.01) and those receiving adjuvant chemotherapy (26% vs. 23%, p<0.01). After matching (n=7.904 in each group), EC was associated with a higher rate of adequate lymphadenectomy (>12 lymph nodes retrieved: 94% vs. 89%, p<0.01). Five-year overall survival did not differ significantly between groups (65.6% for EC vs. 66.9% for SC, p=0.074). However, SC was associated with a modest but statistically significant improvement in CSS (84.3% vs. 81.7%, p<0.01). In adjusted analysis, surgical extent (HR=0.8376, p<0.001), along with age, sex, tumor grade, stage, and lymph node yield, were independently associated with CSS. Conclusion: While EC is more commonly utilized in advanced-stage disease and facilitates higher lymph node retrieval, SC offers comparable-and potentially superior-CSS in selected patients. These findings support the consideration of a tailored surgical strategy based on tumor biology and individual patient characteristics.

Indexed as

extended colectomySEERsegmental colectomysurvivalTransverse colon

Identifiers

PMID41059610
PMCPMC12687387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.