Evidence map›Paper›PMID 41059477›Full record

ArticleFrontiers in pediatrics2025

Neonatal anemia due to spontaneous fetomaternal hemorrhage in a term neonate: a case report of an incidental finding and brief review.

Xinxin Hao, Yuyu Zhang, Chang Gao, Qiushi Wang

Abstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinxin HaoDepartment of Blood Transfusion, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Yuyu ZhangImmunohematology Reference Laboratory, Shanghai Blood Center, Shanghai, China.
Chang GaoDepartment of Blood Transfusion, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Qiushi WangDepartment of Blood Transfusion, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fetomaternal hemorrhage (FMH) is a rare perinatal condition characterized by the transplacental transfer of fetal erythrocytes into the maternal circulation. It poses significant risks, including fetal anemia, hydrops fetalis, and maternal alloimmunization, and often remains underdiagnosed due to non-specific clinical presentations and limited diagnostic accessibility. We present a case of a term neonate delivered via cesarean section at 38 weeks' gestation who exhibited severe anemia and hyperbilirubinemia. Blood group analysis revealed maternal-neonatal Rh incompatibility, while flow cytometry quantified 2.0% fetal erythrocytes in maternal blood. This case underscores the diagnostic value of integrating blood group serology and flow cytometry in FMH confirmation, particularly when standard tests yield equivocal results. A multidisciplinary evaluation of the fetus is the key to early diagnosis and intervention to improve the clinical outcome of perinatal infants.

Indexed as

blood group serologyfetomaternal hemorrhageflow cytometryneonatal anemiaperinatal mortalityRh incompatibility

Identifiers

PMID41059477
PMCPMC12498552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.