Evidence map›Paper›PMID 41059461›Full record

ArticleFrontiers in veterinary science2025

Fermented cottonseed meal improves production performance, immune function and intestinal microecological environment of laying hens and its nutritional properties.

Mingyang Xu, Jia Li, Wei Wang, Tongguo Gao, Caixuan Zhang, Zhimin Hao, Cheng Zhou

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingyang XuCollege of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China.
Jia LiCollege of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China.
Wei WangCollege of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China.
Tongguo GaoCollege of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China.
Caixuan ZhangCollege of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China.
Zhimin HaoCollege of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China.
Cheng ZhouCentral Laboratory, Affiliated Hospital, Hebei University, Baoding, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Global population growth and consumption upgrades have led to an increase in demand for animal feed protein sources, which has prompted an urgent need to find economical alternative protein sources. In this study, the potential of partially replacing traditional protein source soybean meal (SBM) with fermented cottonseed meal (FCSM) in practical applications were evaluated. Methods: The 180 24-week-old Hyland Brown laying hens were randomly divided into a control group (CON, fed SBM) and an experimental group (FCSM, fed FCSM). The effects of FCSM on the production performance, immune system, intestinal morphology and microbiota composition of laying hens were investigated. Furthermore, the enrichment of FCSM for characteristic nutrient metabolites and key pathways was further explored. Results: The feed-to-egg ratio and egg quality indexes (eggshell thickness, eggshell strength, albumen height and Haugh units) of laying hens in the FCSM group were significantly better than those of the CON group ( Conclusion: FCSM promoted the absorption of nutrients and intestinal health in laying hens by regulating the intestinal flora, demonstrating superior efficacy over BSM in overall production performance, immune function, and intestinal morphology. These findings provides a theoretical basis for the resource reuse in CSM and the precise nutrition of laying hens.

Indexed as

feedfermented cottonseed mealintestinal healthlaying hensmetabolomic profilenutrition

Identifiers

PMID41059461
PMCPMC12497634

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.