Evidence map›Paper›PMID 41059395›Full record

ArticleRadiology advances2024

Platelet-rich plasma for patellar tendinopathy: a randomized controlled trial correlating clinical outcomes and quantitative imaging.

Rianne A van der Heijden, Zachary Stewart, Robert Moskwa, Fang Liu, John Wilson, Scott J Hetzel, Darryl Thelen, Bryan Heiderscheit, Richard Kijowski, Kenneth Lee

Abstract read
In one paragraph

Article in Radiology advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rianne A van der HeijdenDepartment of Radiology, University of Wisconsin-Madison, Madison, WI 53792, United States.ORCID https://orcid.org/0000-0001-6964-2536
Zachary StewartDepartment of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02115, United States.
Robert MoskwaDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI 53792, United States.
Fang LiuDepartment of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02115, United States.
John WilsonDepartment of Orthopedics and Rehabilitation, University of Wisconsin, Madison, WI 53792, United States.
Scott J HetzelDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53792, United States.ORCID https://orcid.org/0000-0002-0244-2959
Darryl ThelenDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53792, United States.
Bryan HeiderscheitDepartment of Orthopedics and Rehabilitation, University of Wisconsin, Madison, WI 53792, United States.
Richard KijowskiDepartment of Radiology, New York University Grossman School of Medicine, New York, NY 10016, United States.
Kenneth LeeDepartment of Radiology, University of Wisconsin-Madison, Madison, WI 53792, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patellar tendinopathy is a common overuse injury in active individuals, often with incomplete recovery. Recently, platelet-rich plasma (PRP) treatment has shown promising results. Traditional qualitative markers are not reliable indicators of treatment response. Advanced quantitative imaging, such as ultrashort-echo time (UTE) MRI and US shear-wave elastography may be valuable adjuncts. Purpose: To investigate the clinical outcomes and quantitative imaging changes in adults with symptomatic patellar tendinopathy treated with PRP, needle tenotomy, or sham injection. Materials and Methods: Single-blinded prospective randomized controlled trial from April 2017 until July 2022 with 3 parallel interventions in athletes with symptomatic patellar tendinopathy: PRP, needle tenotomy, and sham injection. Visual analog scale for pain, patella tendinopathy-specific Victorian Institute of Sport Assessment Patella function, conventional US, shear wave speed (SWS), UTE T2* relaxation time (T2* Results: A total of 29 subjects (mean age, 26.1 ± 5.3 years; 82.8% men) were randomized. At 52 weeks, all groups demonstrated a significant improvement in pain, though most pronounced within the PRP group ( Conclusion: Clinical improvement was evident regardless of treatment but was greatest with PRP. SWS correlated with improvement in pain and may represent an adjunctive measure to assess healing in patellar tendinopathy. Correlative changes in T2* UTE quantitative markers suggest their potential for response assessment, but further research is needed to clarify their clinical applicability.

Indexed as

MRI ultrashort TEneedle tenotomypatellar tendinopathyplatelet-rich plasmaquantitativeshear wave elastography

Identifiers

PMID41059395
PMCPMC12481695

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.