Evidence map›Paper›PMID 41059268›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2025

Comprehensive mixed reality surgical navigation system for liver surgery.

Bowen Xiang, Jon S Heiselman, Michael I Miga

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Toward a Surgical Clip-Based Registration Approach for Aligning Pathology Data to Tumor Bed Using Mixed Reality.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bowen XiangVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, United States.ORCID https://orcid.org/0000-0002-6373-0460
Jon S HeiselmanVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, United States.ORCID https://orcid.org/0000-0002-4414-8846
Michael I MigaVanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, United States.ORCID https://orcid.org/0000-0002-0694-9765

Funding

Deformation Corrected Image Guided Laparoscopic Liver SurgeryR01EB027498 · NIBIB · VANDERBILT UNIVERSITY · PI JARNAGIN, WILLIAM ROBERT, MIGA, MICHAEL IAN · 2019 to 2022
$2.5M
NIBIB NIH HHS R01 EB027498
6 · The paper itself

Abstract

Purpose: Intraoperative liver deformation and the need to glance repeatedly between the operative field and a remote monitor undermine the precision and workflow of image-guided liver surgery. Existing mixed reality (MR) prototypes address only isolated aspects of this challenge and lack quantitative validation in deformable anatomy. Approach: We introduce a fully self-contained MR navigation system for liver surgery that runs on a MR headset and bridges this clinical gap by (1) stabilizing holographic content with an external retro-reflective reference tool that defines a fixed world origin, (2) tracking instruments and surface points in real time with the headset's depth camera, and (3) compensating soft-tissue deformation through a weighted ICP + linearized iterative boundary reconstruction pipeline. A lightweight server-client architecture streams deformation-corrected 3D models to the headset and enables hands-free control via voice commands. Results: Validation on a multistate liver-phantom protocol demonstrated that the reference tool reduced mean hologram drift from Conclusions: By unifying stable MR visualization, tool tracking, and biomechanical deformation correction in a single headset, the proposed platform eliminates monitor-related context switching and restores spatial fidelity lost to liver motion. The device-agnostic framework is extendable to open approaches and potentially laparoscopic workflows and other soft-tissue interventions, marking a significant step toward MR-enabled surgical navigation.

Indexed as

augmented realitydeformation correctionimage-guided surgeryliver surgerymixed realitysurgical navigationtracking

Identifiers

PMID41059268
PMCPMC12499930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.