Evidence map›Paper›PMID 41059238›Full record

ArticleBeyoglu eye journal2025

Comparison of the Accuracy, Comprehensiveness, and Readability of ChatGPT, Google Gemini, and Microsoft Copilot on Dry Eye Disease.

Dilan Colak, Burcu Yakut, Abdullah Agin

Abstract read
In one paragraph

Article in Beyoglu eye journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dilan ColakDepartment of Ophthalmology, University of Health Science, Beyoglu Eye Training and Research Hospital, Istanbul, Türkiye.
Burcu YakutDepartment of Ophthalmology, University of Health Science, Haseki Training and Research Hospital, Istanbul, Türkiye.
Abdullah AginDepartment of Ophthalmology, University of Health Science, Haseki Training and Research Hospital, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study compared the performance of ChatGPT, Google Gemini, and Microsoft Copilot in answering 25 questions about dry eye disease and evaluated comprehensiveness, accuracy, and readability metrics. Methods: The artificial intelligence (AI) platforms answered 25 questions derived from the American Academy of Ophthalmology's Eye Health webpage. Three reviewers assigned comprehensiveness (0-5) and accuracy (-2 to 2) scores. Readability metrics included Flesch-Kincaid Grade Level, Flesch Reading Ease Score, sentence/word statistics, and total content measures. Responses were rated by three independent reviewers. Readability metrics were also calculated, and platforms were compared using Kruskal-Wallis and Friedman tests with Results: Google Gemini demonstrated the highest comprehensiveness and accuracy scores, significantly outperforming Microsoft Copilot (p<0.001). ChatGPT produced the most sentences and words (p<0.001), while readability metrics showed no significant differences among models (p>0.05). Inter-observer reliability was highest for Google Gemini (ICC=0.701), followed by ChatGPT (ICC=0.578), with Microsoft Copilot showing the lowest agreement (ICC=0.495). These results indicate Google Gemini's superior performance and consistency, whereas Microsoft Copilot had the weakest overall performance. Conclusion: Google Gemini excelled in content volume while maintaining high comprehensiveness and accuracy, outperforming ChatGPT and Microsoft Copilot in content generation. The platforms displayed comparable readability and linguistic complexity. These findings inform AI tool selection in health-related contexts, emphasizing Google Gemini's strengths in detailed responses. Its superior performance suggests potential utility in clinical and patient-facing applications requiring accurate and comprehensive content.

Indexed as

Artificial intelligenceChatGPTdry eye diseaseGoogle GeminiMicrosoft Copilot

Identifiers

PMID41059238
PMCPMC12499718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.