ArticleFrontiers in sports and active living2025
Effects of a 24-week multicomponent training program on functional capacity, persistent symptoms, body composition, and physical activity in patients significantly affected by COVID-19: the COVID-19 and REhabilitation study (CORE-study)-randomized clinical trial.
Article in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: COVID-19 can lead to reduced functional capacity, loss of muscle mass, and lasting and persistent symptoms, resulting in reduced physical activity. Objective: To evaluate the effects of a multicomponent training on functional capacity, persistent symptoms, body composition, pulmonary function, and physical activity levels in patients significantly impaired by SARS-CoV-2. Methods: The participants were randomly assigned (1:1) to either the intervention group (IG), which received multicomponent training (balance/aerobic/resistance), or the control group (CG). Functional capacity [6 min walk test (6MWT)-primary outcome, sit and reach, sit-to-stand, timed up and go], persistent symptoms (dyspnea, fatigue, post-COVID functional status, frailty), body composition (dual-energy x-ray absorptiometry and bioimpedance), pulmonary function, and physical activity levels (accelerometry) were evaluated at baseline and after 24 weeks. Generalized estimating equations were used, with the significance level set at Results: Forty participants [age = 52.00 (12.93) years, 19 women] were included. The primary outcome 6MWT showed improvement in both groups in the ITT analysis (IG: 35.5 m, 95% CI: -3.0 to 74.1; CG: 37.4 m, 95% CI: -5.26 to 80.2) and in the IG (87.6 m, 95% CI: 50.6-124.4) in the PP analysis. The IG showed a reduction in mental fatigue (-1.7 points, 95% CI: -0.5 to 3.5) and general fatigue (-6.5 points, 95% CI: -9.4 to -3.5) in our ITT analysis. The IG also revealed improvement in timed up and go test (-1.6 s, 95% CI: -2.6 to -0.6), mental fatigue (-2.0points, 95% CI: -3.6 to 0.7), general fatigue (-6.4points, 95% CI: -11.0 to -1.6), and a protective effect against increased body fat in PP analysis. Conclusion: This program was effective in improving fatigue in patients previously significantly affected by COVID-19.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.