In one paragraphArticle in Molecular systems design & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Jennifer A SimonovichJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0000-0002-7731-8872 Arun WanchooJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0000-0002-2770-0221 Ryan A ClarkJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0009-0004-0142-9519 Junha ParkJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0009-0003-2857-8891 Ayumi ShigemotoJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0009-0001-8993-9289 Benjamin G KeselowskyJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0000-0001-6474-7769 Gregory A HudallaJ. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida PO Box 116131 Gainesville FL 32610 USA bgk@ufl.edu ghudalla@bme.ufl.edu +1 (352) 392 9791 +1 (352) 273 9221 +1 (352) 273 5878 +1 (352) 273 9326.ORCID https://orcid.org/0000-0003-2259-0809 Funding
Tissue-Anchored vs. Circulating Engineered Enzyme Constructs for Immunometabolic Resolution of PsoriasisR01AI171045 · NIAID · UNIVERSITY OF FLORIDA · PI Dorina Avram, Benjamin George Keselowsky · 2023 to 2026
$3.1MDiversity Supplement: Directing Tryptophan Immunometabolism to Ameliorate Liver Ischemic-Reperfusion InjuryR01DK129690 · NIDDK · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE, ZARRINPAR, ALI · 2022 to 2025
$2.7MTolerogenic dual microparticle system for treatment of multiple sclerosisR01AI133623 · NIAID · UNIVERSITY OF FLORIDA · PI AVRAM, DORINA, KESELOWSKY, BENJAMIN GEORGE · 2017 to 2021
$2.6MTissue-Targeted Enzyme for Localized Tryptophan Catabolism to Direct Subcutaneous and Oral Mucosal Inflammatory ResponsesR01DE027301 · NIDCR · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE · 2017 to 2020
$2.0MGlycosylation as a Structural Determinant in Peptide FibrillizationR35GM133697 · NIGMS · UNIVERSITY OF FLORIDA · PI HUDALLA, GREGORY · 2019 to 2023
$1.9MDendritic Cell-Targeting Microparticles for Subcellularly-Targeted Delivery of InR01DK091658 · NIDDK · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE · 2012 to 2016
$1.6MBiomaterial Delivery System for Type 1 Diabetes VaccineR01DK098589 · NIDDK · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE · 2014 to 2017
$1.5MModular Nanomedicines Based on Heterogeneous Fusion Protein Co-AssemblyR03EB019684 · NIBIB · UNIVERSITY OF FLORIDA · PI HUDALLA, GREGORY · 2015 to 2016
$141kNIAID NIH HHS R01 AI133623NIAID NIH HHS R01 AI171045NIBIB NIH HHS R03 EB019684NIDCR NIH HHS R01 DE027301NIDDK NIH HHS R01 DK091658NIDDK NIH HHS R01 DK098589NIDDK NIH HHS R01 DK129690NIGMS NIH HHS R35 GM133697
6 · The paper itselfAbstract
Indoleamine 2,3-dioxygenase is an immunomodulatory enzyme that shows great promise when delivered exogenously as a protein therapeutic. However, IDO activity is under complex redox control, mediated in part by multiple cysteine residues within its primary sequence. We have characterized three IDO mutants in which solvent-accessible cysteine residues were mutated to chemically-similar serine residues, "IDO
Identifiers
PMID41059158
PMCPMC12498130
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