Evidence map›Paper›PMID 41058842›Full record

ReviewCureus2025

Patterns of Glomerular Injury: Histopathological Classification and Clinical Correlation.

Hussein Qasim, Mohammad Abu Shugaer, Shaima' Dibian, Mahfouz Ktaifan, Karis Khattab, Matteo Luigi Giuseppe Leoni, Giustino Varrassi

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hussein QasimDepartment of Pathology and Laboratory Medicine, Jordan University of Science and Technology, Irbid, JOR.
Mohammad Abu ShugaerDepartment of Pathology and Laboratory Medicine, Jordan University of Science and Technology, Irbid, JOR.
Shaima' DibianDepartment of Pathology and Laboratory Medicine, Jordan University of Science and Technology, Irbid, JOR.
Mahfouz KtaifanDepartment of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, PSE.
Karis KhattabFaculty of Medicine, Jordan University of Science and Technology, Irbid, JOR.
Matteo Luigi Giuseppe LeoniDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University, Rome, ITA.
Giustino VarrassiDepartment of Pain Medicine, Fondazione Paolo Procacci, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomerular diseases represent a diverse group of conditions that significantly contribute to chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide. Understanding the histopathological patterns of glomerular injury is essential for accurate diagnosis, prognosis, and targeted therapy. This comprehensive review explores the morphologic, immunopathologic, and clinical characteristics of major glomerular disorders, including minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, immunoglobulin A nephropathy, lupus nephritis, and others. Histological classification is integrated with clinical syndromes, such as nephrotic and nephritic presentations, emphasizing the role of light microscopy, immunofluorescence, and electron microscopy in renal biopsy interpretation. Recent advances in molecular diagnostics, digital pathology, and artificial intelligence are also discussed, highlighting their transformative impact on precision nephrology. Through a multidisciplinary lens, this review underscores the prognostic and therapeutic implications of distinct histologic patterns and advocates for the continued evolution of clinicopathologic correlation in glomerular disease management.

Indexed as

glomerular diseasehistopathologyimmunofluorescencenephritic syndromenephrotic syndromerenal biopsy

Identifiers

PMID41058842
PMCPMC12499900

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.