Evidence map›Paper›PMID 41058807›Full record

ArticleCureus2025

Delayed Diagnosis of Coarctation of the Aorta as a Cause of Secondary Hypertension in an Adult Female With Congenital Heart Disease: A Missed Opportunity for an Earlier Diagnosis?

Kamran D Ahmad, Ellie Anderson, Zahid Khan, Shah R Mohdnazri

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamran D AhmadCardiology, Mid and South Essex NHS Foundation Trust, Southend-on-Sea, GBR.
Ellie AndersonCardiology, Southend University Hospital, Southend-on-Sea, GBR.
Zahid KhanCardiology, University of South Wales, Pontypridd, GBR.
Shah R MohdnazriCardiology, Mid and South Essex NHS Foundation Trust, Southend University Hospital, Southend-on-Sea, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coarctation of the aorta (CoA) is a narrowing of the aorta that typically occurs just after the point where the left subclavian artery branches off. This is usually around the area where the ductus arteriosus used to connect to the aorta in foetal life. Most cases are sporadic; however, genetic associations have also been established in some cases. Generally, it leads to heart failure symptoms at an early age, but later presentation beyond adulthood often remains asymptomatic. Clinical suspicion about the condition usually arises in patients with uncontrolled blood pressure and reduced or absent femoral pulses. We present a case of a 30-year-old female patient known to have congenital heart disease (ventricular septal defect and moderate tricuspid regurgitation) who suffered from infective endocarditis in her adolescent years (treated successfully medically) and presented years later with uncontrolled blood pressure, palpitations, and headaches. With the help of a workup for hypertension in the young, especially imaging, and a close follow-up, she was diagnosed with CoA, which has a strong association with other congenital heart diseases. She underwent stenting of the lesion, with a successful outcome and reasonable control of blood pressure.

Indexed as

bicuspid aortic valve diseasecoa: aortic coarctationcoa (coarctation of the aorta)coarctation stentinfective endocarditisresistant hypertensionsevere coarctation of the aortasevere hypertensionstenting aortaventricular septal defect (vsd)

Identifiers

PMID41058807
PMCPMC12499942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.