ReviewCureus2025
Outcomes of Total Ankle Arthroplasty in Non-traumatic Arthritis Versus Post-traumatic Arthritis: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this review is to compare the outcomes of total ankle arthroplasty in patients with ankle arthritis without previous ankle trauma or intervention versus patients with post-traumatic arthritis. Further analysis was performed to review the outcomes of ankle arthroplasty irrespective of the patients' cohorts. A comprehensive literature search of Embase, Ovid Medline, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Ovid Emcare and Cochrane, Turning Research Into Practice (TRIP) databases. In total, 17 studies met the inclusion criteria. Continuous data were pooled using the mean difference with a 95% Confidence interval. Dichotomous data were pooled as a risk ratio with a 95% Confidence interval, both using the Inverse variance random effect model. The pooled analysis indicates a revision rate of 4.2% (14 of 330 patients) in the ankle arthritis without previous trauma or intervention group (POA) compared to 11.8% (29 of 245 patients) in the post-traumatic arthritis group (PTOA). There was no statistical difference in the American Orthopaedic Foot and Ankle Society (AOFAS) score between POA and PTOA groups (MD=1.0, 95% CI: 4.4 to 6.4) and no statistically significant difference in the complication rates between POA and PTOA (RR=0.79, 95% CI: 0.59 to 1.07). This meta-analysis demonstrates that total ankle arthroplasty in patients with prior surgical intervention for post-traumatic arthritis is associated with higher revision rates than in patients without previous intervention. However, they might still yield a similar functional outcome in the short term. The role of total ankle arthroplasty should be clearly defined, weighing risks against patient expectations, with longitudinal studies needed to further clarify such risks and benefits.
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