Evidence map›Paper›PMID 41058757›Full record

ReviewThe journal of venomous animals and toxins including tropical diseases2025

Therapeutic potential of iron oxide nanoparticles for cutaneous leishmaniasis: a systematic review of

Priscila de Cássia da Silva, Bruna de Macedo Lima, Camila Sales Nascimento, Anna Carolina Pinheiro Lage, Celso Pinto de Melo, Carlos Eduardo Calzavara-Silva, Érica Alessandra Rocha Alves

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of venomous animals and toxins including tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Priscila de Cássia da SilvaCellular and Molecular Immunology Research Group, René Rachou Institute, Oswaldo Cruz Foundation (Fiocruz Minas), Belo Horizonte, MG, Brazil.
Bruna de Macedo LimaCellular and Molecular Immunology Research Group, René Rachou Institute, Oswaldo Cruz Foundation (Fiocruz Minas), Belo Horizonte, MG, Brazil.
Camila Sales NascimentoCellular and Molecular Immunology Research Group, René Rachou Institute, Oswaldo Cruz Foundation (Fiocruz Minas), Belo Horizonte, MG, Brazil.
Anna Carolina Pinheiro LageBiotechnology Applied to the Study of Pathogens Research Group, René Rachou Institute, Oswaldo Cruz Foundation (Fiocruz Minas), Belo Horizonte, MG, Brazil.
Celso Pinto de MeloNon-Conventional Polymers Group, Department of Physics, Federal University of Pernambuco, Recife, PE, Brazil.
Carlos Eduardo Calzavara-SilvaCellular and Molecular Immunology Research Group, René Rachou Institute, Oswaldo Cruz Foundation (Fiocruz Minas), Belo Horizonte, MG, Brazil.
Érica Alessandra Rocha AlvesCellular and Molecular Immunology Research Group, René Rachou Institute, Oswaldo Cruz Foundation (Fiocruz Minas), Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-9184-6532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of cutaneous leishmaniasis (CL) is challenged by limited therapeutic options, high drug toxicity, and frequent treatment failure. In this context, iron oxide nanoparticles (IONPs) have emerged as promising therapeutic alternatives. This review summarizes experimental findings on the

Indexed as

Antiprotozoal agentsCutaneous leishmaniasisIron oxideLeishmaniaNanomedicineNanoparticlesSystematic review

Identifiers

PMID41058757
PMCPMC12500319

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.