ReviewSmall science2025
Developments of Thermosensitive Hydrogel for Maxillofacial Bone Regeneration.
Review in Small science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exploring the potential of vanadium(IV) complex in autophagy activation: structural modifications, NMR calculations, and novel interactions with PI3Kγ.Journal of molecular modeling · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maxillofacial bone defects usually lead to facial deformities and multifunctional impairments, which tremendously damage patients' mental health and social functioning. Recently, the thermosensitive hydrogel combined with seed cells and growth factors has offered a novel approach for maxillofacial bone regeneration. Remarkably responsive to external temperature changes, thermosensitive hydrogel can transform between sol and gel states. Furthermore, its unique properties, such as fluidity, minimally invasive injectability, localized applicability, and controllable drug release, have been increasingly recognized, endowing it with significant promise in bone regeneration. Cutting-edge research on the effects of thermosensitive hydrogels has been reviewed. However, the mechanisms involved in promoting bone regeneration in the maxillofacial region have not yet been established. This article represents the first review of the specific mechanism of thermosensitive hydrogel in angiogenesis and neurogenesis, specifically focusing on its role in maxillofacial osteogenesis. Finally, the article examines the scaffold and drug delivery capabilities of thermosensitive hydrogel in maxillofacial osteogenesis. This review is expected to provide some insights into the advanced developments of thermosensitive hydrogel for maxillofacial bone regeneration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.