Evidence map›Paper›PMID 41058589›Full record

Trial reportHead & neck2026

Effect of a Home-Based Exercise Program on Muscle Mass, Fatigue, and Health-Related Quality of Life Among Patients with Oral Cancer: A Randomized Trial.

Camilla Wallmander, Ingvar Bosaeus, Ewa Silander, Hedda Haugen Cange, Jan Nyman, Monika Fagevik Olsén, Elisabet Blomsterwall, Malin Berg, Eva Hammerlid

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Camilla WallmanderDepartment of Otorhinolaryngology-Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0009-0000-1431-1051
Ingvar BosaeusDepartment of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ewa SilanderDepartment of Otorhinolaryngology-Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hedda Haugen CangeDepartment of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jan NymanDepartment of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Monika Fagevik OlsénDepartment of Neuroscience and Physiology/Health and Rehabilitation/Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-0207-4105
Elisabet BlomsterwallDepartment of Otorhinolaryngology-Head and Neck Surgery, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
Malin BergDepartment of Otorhinolaryngology-Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Eva HammerlidDepartment of Otorhinolaryngology-Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

Local Research and Development Council Gothenburg and Södra Bohuslän VGFOUGSB-1004575Operational Healthcare Committee, Region Västra Götaland in Sweden VGFOUREG-750821Sahlgrenska University Hospitals Research Foundations Västra Götaland, Sweden SU-997896Swedish state under the agreement between the Swedish government and the county councils Västra Götaland Region, the ALF agreement ALFGBG-965352
6 · The paper itself

Abstract

backgroundPatients with head and neck cancer (HNC) often experience deteriorated health-related quality of life (HRQoL) and loss of body weight and muscle mass. The primary aim was to determine if a home-based exercise program, aiming to increase physical activity (PA), could reduce muscle mass loss and fatigue.

methodsOral cancer patients were randomized to an exercise group (EG) or a control group (CG). The EG received a home-based exercise program, and both groups were followed for 1 year. The Frändin/Grimby activity scale, bioelectrical impedance analysis, and HRQoL questionnaires were used to assess PA, muscle mass, and fatigue.

resultsIn total, 119 patients were included. The EG increased their PA, but no differences in muscle mass were found between groups. A tendency toward less fatigue and better global QoL was observed in the EG.

conclusionFuture studies are needed to explore the possible benefits of PA in patients with HNC.

Indexed as

Exercise TherapyFatigueMouth NeoplasmsQuality of LifeAdultAgedFemaleHome Care ServicesHumansMaleMiddle AgedMuscle, SkeletalSurveys and QuestionnairesTreatment Outcomeexercise programfatiguemuscle massoral cancerphysical activity

Identifiers

PMID41058589
PMCPMC12891755

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.