ArticleMedical physics2025
Development and dosimetric verification of static SHArc: Step-and-shoot carbon ion arc therapy for LET
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarbon ion radiotherapy (CIRT) offers higher linear energy transfer (LET) and superior relative biological effectiveness, making it a promising option for treating hypoxic, radioresistant tumors. Spot-scanning Hadron Arc (SHArc) therapy enables dose-averaged LET (LET PURPOSE: This work establishes the first step-and-shoot planning and delivery technique for carbon ion arc therapy (static SHArc) at the Heidelberg Ion-beam Therapy Center using the gantry system. Static SHArc therapy is evaluated in terms of plan quality and delivery feasibility for pancreatic cancer.
methodsStatic SHArc plans were optimized for seven pancreatic cancer cases, considering 20 gantry angles. Two distinct energy layer (EL) selection techniques were investigated: (1) Central EL, selecting the seven central ELs per beam, and (2) MU-Based EL, prioritizing ELs contributing the highest monitor units (MU). LET
resultsStatic SHArc plans improved LET
conclusionsThis study investigates static SHArc, a step-and-shoot approach for delivering carbon ion arc therapy. While static SHArc can provide dosimetric advantages, particularly in terms of LET
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.