ArticleMedical physics2025
Three-dimensional noise characteristics of clinical photon counting detector CT.
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A physics primer on photon-counting detectors in CT: Physics, signal formation, and performance.Medical physics · 2026Review
- Assessment of Image Quality Performance of a Photon-Counting Computed Tomography Scanner Approved for Whole-Body Clinical Applications.Sensors (Basel, Switzerland) · 2025Article
- Three-dimensional noise characteristics of clinical photon counting detector CT.Medical physics · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince the introduction of whole-body photon-counting detector CT (PCD-CT) into clinical practice, extensive physics assessments have been conducted to elucidate its image quality advantages over energy-integrating detector CT (EID-CT) and to support its clinical adoption. However, evaluations of its three-dimensional (3D) noise power spectrum (NPS), which simultaneously quantifies in-plane and through-plane noise texture and magnitude, remain limited. PURPOSE: To experimentally evaluate the 3D NPS of an NAEOTOM Alpha PCD-CT system and its dependence on scan mode, reconstruction image type, quantum iterative reconstruction (QIR) strength, mono-energy (keV) level, spiral pitch, and radiation dose.
methodsRepeated scans of a 20 cm water phantom and a 30 cm PMMA phantom were conducted under the clinical Standard mode, clinical Ultra-High-Resolution (UHR) mode, and an Expert Service mode. Reconstructed image types include T3D, virtual monoenergetic image (VMI), and T1 (a linear reconstruction of total-energy bin available via the Expert Service mode). Data were collected at seven dose levels (0.4-24 mGy) and four spiral pitch levels (0.35-1.5). T3D and VMI images were reconstructed with varying QIR strengths, and VMIs were reconstructed at energies ranging from 40 to 190 keV. The 3D NPS,
results
conclusionThe 3D NPS provides new insight into the noise characteristics of PCD-CT: Noise in the native PCD-CT projection data is uncorrelated across detector rows, but clinical reconstruction processes introduce noise spatial correlation along both axial and z directions, particularly at higher QIR strengths, lower radiation doses, or with larger image objects that increase the percentage of scattered photons. Compared to the Standard mode, UHR mode reconstruction exhibits stronger noise correlation due to its superior detector spatial resolution, allowing for more aggressive spatial smoothing to achieve the desired spatial resolution in the final image.
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