ArticleAnnals of medicine2025
Temporal trends and machine learning prediction for chronic kidney disease due to hypertension in young adults from 1990 to 2021: an analysis of the global burden of disease study 2021.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Artificial Intelligence in Cardiovascular Medicine: Focus on Hypertension.Hypertension (Dallas, Tex. : 1979) · 2026Pooled it
- Mechanistic Insights into the Antihypertensive and Cardioprotective Actions of Corosolic Acid: A Narrative Review.Molecules (Basel, Switzerland) · 2026Review
- Cardiovascular-kidney-metabolic syndrome stages and increased risk of all-cause and cause-specific mortality in UK Biobank.American journal of preventive cardiology · 2026Article
- Multi-dimensional sleep patterns predict complications and mortality in chronic kidney disease patients: a prospective study from the UK Biobank.Frontiers in public health · 2026Article
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5 authors.
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Abstract
backgroundYoung adults aged 25-49, at the peak of work and family responsibilities, face serious health and productivity challenges when affected by chronic kidney disease (CKD) due to hypertension.
methodsUsing Global Burden of Disease (GBD) 1990-2021 data, we assessed global, regional, and national CKD burden due to hypertension in young adults, focusing on mortality and disability-adjusted life years (DALYs). Trends analyzed by Joinpoint regression and forecasted to 2040 using eight machine learning models.
resultsIn 2021, global mortality from CKD due to hypertension reached 18,675.24 cases, a 157.55% increase since 1990. The age-standardized mortality rate (ASMR) rose from 0.31 to 0.45 per 100,000 persons, with an average annual percentage change (AAPC) of 1.24% (
conclusionsCKD due to hypertension is a growing global challenge in young adults. Substantial heterogeneity exists in the disease burden and its temporal trends across countries and regions, highlighting the strong distributive inequities of CKD worldwide.
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