ArticleJournal of clinical apheresis2025
Chronic Kidney Disease Is a Risk Factor for the Development of Hyperchloremic Metabolic Acidosis After Repeated Therapeutic Plasma Exchanges.
Article in Journal of clinical apheresis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Unveiling the Potential of Fish Swim Bladder-Derived Biomaterials in Urological Care.Advances in urology · 2026Review
- Chronic Kidney Disease Is a Risk Factor for the Development of Hyperchloremic Metabolic Acidosis After Repeated Therapeutic Plasma Exchanges.Journal of clinical apheresis · 2025Article
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Authors and funding
3 authors.
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Abstract
Hyperchloremic metabolic acidosis is an underreported but common metabolic complication following therapeutic plasma exchange (TPE) with an albumin-saline solution, particularly when multiple TPE sessions are performed within a limited period. The risk of hyperchloremic metabolic acidosis may be the highest in patients with chronic kidney disease because of their limited acid excretion capacity. We prospectively collected data from all patients who received TPE at Amsterdam UMC between February 2023 and March 2025. We collected data on demographics, TPE-related parameters, and blood electrolyte concentrations. We investigated the effect of TPE on plasma sodium, chloride, and bicarbonate concentrations, the occurrence of adverse events, and the modulating role of kidney function. Data from 64 patients with 320 TPE sessions were included in the analysis. The mean age was 50 years, 55% of the patients were male and the mean eGFR was 35 mL/min/1.73 m
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