Evidence map›Paper›PMID 41058047›Full record

ArticleThoracic cancer2025

Diffuse Pulmonary Meningotheliomatosis Presenting as Innumerable Pulmonary Micronodules: A Case Report.

Eitetsu Koh, Yasuo Sekine, Hodaka Oeda, Tadao Nakazawa

Abstract readCase Reports
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eitetsu KohDepartment of Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan.ORCID https://orcid.org/0009-0004-8983-9239
Yasuo SekineDepartment of Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan.
Hodaka OedaDepartment of Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan.
Tadao NakazawaDepartment of Pathology, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan.ORCID https://orcid.org/0000-0001-8415-4573

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse pulmonary meningotheliomatosis (DPM) is a rare lung condition characterized by widespread meningothelial-like nodules and may radiologically mimic metastatic or granulomatous disease. We report a 2019-onset case of a 44-year-old woman with incidentally detected, bilateral 1-2-mm pulmonary micronodules on screening CT. Laboratory tests and pulmonary function were normal. Owing to the minute, peripheral distribution of the nodules, bronchoscopic biopsy was not feasible, and diagnostic video-assisted thoracoscopic wedge resection was undertaken. Histology showed spindle-to-ovoid cells in whorled arrangements without atypia or mitoses. Immunohistochemistry revealed diffuse vimentin positivity and negativity for epithelial and neuroendocrine markers (EMA, cytokeratin AE1/AE3, SMA, chromogranin). Postoperative brain MRI showed no intracranial lesion. The patient has remained asymptomatic without radiologic progression over 3 years. This case underscores DPM as an uncommon yet important differential diagnosis of diffuse pulmonary micronodules and highlights the need for histopathologic confirmation when bronchoscopic sampling is impracticable. Where available, PR and SSTR2A immunostains may further support the diagnosis.

Indexed as

Lung NeoplasmsAdultDiagnosis, DifferentialFemaleHumans

Identifiers

PMID41058047
PMCPMC12504144

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.