Evidence map›Paper›PMID 41057904›Full record

ArticleBMC medical informatics and decision making2025

Design and implementation of a natural language processing system at the point of care: MiADE (medical information AI data extractor).

Jennifer Jiang-Kells, James Brandreth, Leilei Zhu, Jack Ross, Yogini Jani, Enrico Costanza, Maisarah Amran, Zeljko Kraljevic, Xi Bai, M M N S Dilan and 6 more

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jennifer Jiang-Kells *Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK. jennifer.jiang.13@ucl.ac.uk.
James Brandreth *Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.
Leilei ZhuClinical and Research Informatics Unit, National Institute for Health and Care Research University College London Hospitals Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, UK.
Jack RossCentre for Medicines Optimisation Research & Education, University College London Hospitals NHS Foundation Trust, London, UK.
Yogini JaniResearch Department of Practice and Policy, University College London School of Pharmacy, London, UK.
Enrico CostanzaUniversity College London Interaction Centre (UCLIC), University College London, London, UK.
Maisarah AmranCentre for Medicines Optimisation Research & Education, University College London Hospitals NHS Foundation Trust, London, UK.
Zeljko KraljevicNational Institute for Health and Care Research Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK.
Xi BaiInstitute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.
M M N S DilanPostgraduate Institute of Medicine, Colombo, Sri Lanka.
Jayathri WijayarathnePostgraduate Institute of Medicine, Colombo, Sri Lanka.
Ravi WickramaratnePostgraduate Institute of Medicine, Colombo, Sri Lanka.
Folkert W AsselbergsInstitute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.
Richard J B DobsonInstitute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.
Wai Keong Wong *Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Anoop D Shah *Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.

Funding

NIHR National Institute of Health Research NIH-R204297
6 · The paper itself

Abstract

backgroundWell-organised electronic health records (EHR) are essential for high quality patient care, but EHR user interfaces can be cumbersome for entry of structured information, resulting in the majority of information being in free text rather than a structured form. This makes it difficult to retrieve information for clinical purposes and limits the research potential of the data. Natural language processing (NLP) at the point of care has been suggested as a way of improving data quality and completeness, but there is little evidence as to its effectiveness. We sought to generate such evidence by developing an open source, modular, configurable NLP system called MiADE, which is designed to integrate with an EHR. This paper describes the design of MiADE and the deployment at University College London Hospitals (UCLH), and is intended to benefit those who may wish to develop or implement a similar system elsewhere.

resultsThe MiADE system includes components to extract diagnoses, medications and allergies from a clinical note, and communicate with an EHR system in real time using Health Level 7 Clinical Document Architecture (HL7 CDA) messaging. This enables NLP results to be displayed to a clinician for verification before saving them to the patient's record. MiADE utilises the MedCAT library (part of the Cogstack family of NLP tools) for named entity recognition (NER) and linking to SNOMED CT, as well as context detection. MedCAT models underwent unsupervised and supervised training on patient notes from UCLH, achieving precision of 83.2% (95% CI 77.0, 88.1), and recall of 85.2% (95% CI 79.1, 89.8) for detection of diagnosis concepts. In simulation testing we found that MiADE reduced the time taken for clinicians to enter structured problem lists by 89%. We have commenced a trial implementation of MiADE at UCLH in live clinical use, integrated with the Epic EHR at UCLH.

conclusionsWe have developed an open source point of care NLP system and successfully integrated it with the EHR in live clinical use at a major hospital. Simulation testing has shown that our system significantly reduces the time taken for clinicians to enter structured diagnosis codes.

Indexed as

Artificial IntelligenceElectronic Health RecordsNatural Language ProcessingPoint-of-Care SystemsHumansDiagnosesnatural language processingpoint of careSNOMED CTTerminology

Identifiers

PMID41057904
PMCPMC12506320

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.