SynthesisBMC pediatrics2025
The impact of physical activity interventions on body composition and quality of life in adolescents with anorexia nervosa: a meta-analysis of randomized controlled trials.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Cognitive Behavioral Therapy Reduces Symptom Severity and Normalizes Neurophysiological and Attentional Reactivity in Anorexia Nervosa: A Randomized Controlled Trial.Brain sciences · 2026Article
- Cyberbullying and Problematic Internet Use as Correlates of Eating-Disorder Symptomatology and Health-Related Quality of Life in Women Under Specialized Care.Healthcare (Basel, Switzerland) · 2026Article
- Digital health literacy and disordered eating among adolescents: the chain mediating roles of physical activity and problematic social media use.Frontiers in psychiatry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveThis study systematically evaluated the effects of exercise interventions on adolescents diagnosed with anorexia nervosa (AN), focusing on key outcomes such as body composition, skeletal muscle metrics, and quality of life. Additionally, this study aimed to identify the most effective intervention protocol.
methodsA comprehensive literature search was conducted across multiple databases, including PubMed, Web of Science, Embase, Scopus, the Cochrane Library, the China Biomedical Literature Database, CNKI, the Wanfang Database, and the VIP Database. Eligible studies included randomized controlled trials (RCTs) examining the impact of exercise interventions on adolescents with AN. Meta-analyses and systematic reviews were performed via RevMan 5.4 and Stata 15 software.
resultsA total of seven RCTs involving 211 adolescent patients were included. Compared with the control interventions, exercise interventions did not significantly affect body mass index (BMI), fat mass, or lean body mass compared to control groups (all P > 0.05). However, significant improvements were observed in weight, thigh muscle circumference, mid-thigh skinfold thickness, and overall quality of life (as measured by the SF-36 scale) (all P < 0.05). Subgroup analysis revealed that an 8-week exercise program, with three sessions per week lasting approximately 50 min each, significantly improved body weight (P < 0.05). Variations in frequency, duration, or intervention period did not significantly affect BMI (all P > 0.05). Notably, combining aerobic and anaerobic exercise had a significant effect on BMI (P < 0.05), although no significant improvements were found in the 10 subdimensions of the SF-36 quality of life scale (all P > 0.05).
conclusionExercise interventions benefit adolescents with AN, particularly by supporting weight recovery, increasing thigh muscle circumference, improving skinfold thickness, and enhancing quality of life. An 8-week programme combining aerobic and anaerobic exercise (three sessions per week, 50 min per session) significantly promoted weight recovery and improved BMI. These findings underscore the importance of personalized exercise interventions to optimize body composition, skeletal muscle health, and quality of life in adolescents with AN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.