Evidence map›Paper›PMID 41057837›Full record

ArticleBMC nephrology2025

Acute kidney injury in a cardiac ICU in a middle-income country: risk factors and outcomes from Thailand.

Supassara Nimkulrat, Nitcha Suphatheerawatr, Punnawit Laungchuaychok, Ukrit Prajantasen, Sathit Kurathong, Wanjak Pongsittisak, Solos Jaturapisanukul

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Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Supassara NimkulratDepartment of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Nitcha SuphatheerawatrNephrology and Renal Replacement Therapy Division, Department of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Punnawit LaungchuaychokNephrology and Renal Replacement Therapy Division, Department of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Ukrit PrajantasenNephrology and Renal Replacement Therapy Division, Department of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Sathit KurathongNephrology and Renal Replacement Therapy Division, Department of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Wanjak PongsittisakNephrology and Renal Replacement Therapy Division, Department of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Solos JaturapisanukulNephrology and Renal Replacement Therapy Division, Department of Internal Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand. Solos@nmu.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is associated with significant morbidity and mortality in critically ill patients. However, data on AKI in coronary care units (CCU) remain limited, particularly in low- and middle-income countries. This study aimed to determine the incidence, etiology, risk factors, and outcomes of AKI in a CCU setting in Thailand.

methodsIn this retrospective cohort study, we analyzed 209 patients admitted to a tertiary hospital CCU between January 2019 and September 2020. We collected data on baseline characteristics, comorbidities, medications, clinical parameters, and outcomes. Risk factors were assessed using multivariable logistic regression analysis.

resultsAKI occurred in 30.6% of patients, with multifactorial etiologies being the most common (42.2%). AKI was associated with significantly higher mortality at both 30 days (35.9% vs. 3.4%, p < 0.001) and 90 days (43.8% vs. 6.9%, p < 0.001). Independent risk factors for AKI included pre-existing chronic kidney disease (adjusted OR 3.47), reduced left ventricular ejection fraction (OR 3.19), mechanical ventilation (OR 3.08), and vasopressor use (OR 2.84). Independent predictors of kidney replacement therapy were mechanical ventilation (OR 11.26) and vasopressor use (OR 5.61).

conclusionsAKI is a frequent and severe complication among CCU patients in a low- to middle-income country, significantly increasing short-term mortality and hospital stay. Early identification of high-risk patients may improve outcomes through timely intervention and monitoring.

Indexed as

Acute Kidney InjuryCoronary Care UnitsAgedDeveloping CountriesFemaleHospital MortalityHumansIncidenceMaleMiddle AgedRenal Replacement TherapyRespiration, ArtificialRetrospective StudiesRisk FactorsThailandAcute kidney injuryCoronary care unitHeart failure

Identifiers

PMID41057837
PMCPMC12505582

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.