Evidence map›Paper›PMID 41057769›Full record

ArticleBMC gastroenterology2025

Small bowel diverticular disease: are we clinically aware?

Yujen Tseng, Jiayinaer Bolatihan, Xiao Li, Jiajing Yu, Dou Wang, Yuqin Jin, Lili Ma, Zhongguang Luo

Abstract readMulticenter Study
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yujen Tseng *Department of Digestive Diseases, Huashan Hospital, Fudan University, 12 Wulimuqi Middle Road, Shanghai, 200040, China.
Jiayinaer Bolatihan *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 Fenglin Road, 200032, Shanghai, China.
Xiao Li *Department of Digestive Diseases, Huashan Hospital, Fudan University, 12 Wulimuqi Middle Road, Shanghai, 200040, China.
Jiajing YuDepartment of Nursing, Huashan Hospital, Fudan University, 12 Wulimuqi Middle Road, Shanghai, 200040, China.
Dou WangDepartment of Gastroenterology, People's Hospital of Shigatse, Tibet, China.
Yuqin JinDepartment of Nursing, Huashan Hospital, Fudan University, 12 Wulimuqi Middle Road, Shanghai, 200040, China. jinyuqinjojo@sina.com.
Lili MaEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 Fenglin Road, 200032, Shanghai, China. ma.lili@zs-hospital.sh.cn.
Zhongguang LuoDepartment of Digestive Diseases, Huashan Hospital, Fudan University, 12 Wulimuqi Middle Road, Shanghai, 200040, China. luozg8@126.com.

Funding

National Natural Science Foundation of China 82172557Natural Science Foundation of Shanghai 21ZR1447600Shanghai "Rising Stars of Medical Talents" Youth Development Program SHWSRS (2025) _071
6 · The paper itself

Abstract

BACKGROUND &

objectiveSmall bowel diverticulum (SBD) is an outpouching of the small intestinal wall and is often neglected in clinical practice due to its undiscerning location. Majority of SBD can be asymptomatic but can also be associated with life-threatening complications. We hereby performed a clinical analysis to investigate the characteristics associated with SBD. PATIENTS AND

methodsThis retrospective case series analyzed clinical data from two tertiary referral centers. Clinical data including baseline characteristics, clinical presentation, diagnostic methods and treatment were systematically collected and reviewed. Subgroup analysis based on distinct location of the SBD, such as the duodenum, jejunum and ileum were also performed.

resultsA total of 149 cases of SBD were ultimately included in the present study analysis. Among 114 duodenal SBD cases, 42 (36.8%) were asymptomatic, while 58 (50.9%) presented with pain/discomfort. In contrast, jejunoileal SBD (n = 35) were predominantly symptomatic: 21 (60.0%) required surgical intervention due to complications such as obstruction (n = 8), bleeding (n = 12), or perforation (n = 5). Endoscopic modalities (DBE/VCE) achieved a diagnostic accuracy of 92.3% for jejunoileal SBD, surpassing radiological methods (CT/BaFT) at 38.5% (p < 0.001). Distinctive case highlights also provided examples of SBD found at different locations.

conclusionSmall bowel diverticular (SBD) disease is often overlooked in clinical practice, due to its discrete location and limited access. With continuous diagnostic advancements, including endoscopic techniques, the detection of SBD is expected to rise, gaining clinical awareness amongst gastroenterologists.

Indexed as

Diverticular DiseasesDiverticulumDuodenal DiseasesIleal DiseasesIntestine, SmallJejunal DiseasesAbdominal PainAdultAgedAged, 80 and overEndoscopy, GastrointestinalFemaleHumansMaleMiddle AgedRetrospective StudiesSmall Bowel Diverticula, Endoscopic Treatment, Double-balloon Enteroscopy, Small Intestinal Bleeding

Identifiers

PMID41057769
PMCPMC12506520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.