Evidence map›Paper›PMID 41057735›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Identifying gaps and needs in care for adolescents and young adults with melanoma.

Reece Moore, Nabeel Ahmad, Miriam Kadosh, Ryann Daniels, Clark Andersen, Michael Roth, Kelly Nelson

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reece MooreMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Nabeel AhmadUniversity of Houston College of Medicine, Houston, TX, USA.
Miriam KadoshMelanoma Research Foundation, Washington D.C., USA.
Ryann DanielsMelanoma Research Foundation, Washington D.C., USA.
Clark AndersenUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael RothUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Kelly NelsonUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA. kcnelson1@mdanderson.org.

Funding

National Institutes of Health and National Cancer Institute R25CA056452
6 · The paper itself

Abstract

purposeAdolescents and young adults (AYAs, age 15-39 years) with melanoma have needs unique from pediatric or adult populations due to interference with developmental milestones. This study aims to assess the needs of AYA melanoma patients using the Needs Assessment and Service Bridge (NA-SB) questionnaire.

methodsA REDCap survey based on the AYA NA-SB was distributed via email, social media, newsletters, and conferences between August to October 2024. Data were reported for the overall population and analyzed by sex, treatment phase, and exposure to immune checkpoint blockers (ICBs).

resultsOne hundred fifty-two patients participated in the survey. Male and female AYAs had different need profiles, with the males expressing greater need in understanding the role of genetics in diagnosis (51.5% vs. 33.9%, p = 0.019) and the sexual side effects of treatment (38.3% vs. 16.6%, p = 0.016) and the females reporting greater needs in understanding their disease status (71.3% vs. 48.5%, p = 0.003). AYAs on active treatment reported greater needs than those who completed treatment in managing work and life during treatment (55.5% vs. 27.1%, p = 0.03), being equipped to cope with diagnosis (42.8% vs. 25%, p = 0.029), and managing the emotional side effects of treatment (62% vs. 29.5%, p = 0.002). AYAs treated with ICBs had greater needs in managing long-term side effects of treatment (70.8% vs. 31.6%, p = 0.0005), pain management (30.6% vs. 11.6%, p = 0.01), and the physical side effects of treatment (36.7% vs. 16.5%, p = 0.021).

conclusionAYA melanoma patients express unique needs based on sex, treatment phase, and type of systemic therapy. Assessing patient needs and connecting AYAs to relevant supportive services may help mitigate unique challenges encountered during melanoma treatment and in post-treatment survivorship.

Indexed as

Health Services Needs and DemandMelanomaNeeds AssessmentSkin NeoplasmsAdolescentAdultFemaleHumansImmune Checkpoint InhibitorsMaleSex FactorsSurveys and QuestionnairesYoung AdultImmune Checkpoint InhibitorsAdolescent and young adultsCancerImmune checkpoint blockersMelanomaNeeds assessment

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.