Evidence map›Paper›PMID 41057637›Full record

ArticleScientific reports2025

Deep intelligence: a four-stage deep network for accurate brain tumor segmentation.

Nirmala Paramanandham, Kishore Rajendiran, L K Pavithra, M Niranjan, Tom Michael Shibu, Ashwin Santosh, Aakash Kumar

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Nirmala ParamanandhamVellore Institute of technology, Chennai Campus, Chennai, India. nirmala.p@vit.ac.in.
Kishore RajendiranSri Sivasubramaniya Nadar College of Engineering, Kalavakkam, India.
L K PavithraVellore Institute of technology, Chennai Campus, Chennai, India.
M NiranjanVisual Computing, Saarland University, Saarbrücken, Germany.
Tom Michael ShibuVellore Institute of technology, Chennai Campus, Chennai, India.
Ashwin SantoshVellore Institute of technology, Chennai Campus, Chennai, India.
Aakash KumarVellore Institute of technology, Chennai Campus, Chennai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Image segmentation is an essential research field in image processing that has developed from traditional processing techniques to modern deep learning methods. In medical image processing, the primary goal of the segmentation process is to segment organs, lesions or tumors. Segmentation of tumors in the brain is a difficult task due to the vast variations in the intensity and size of gliomas. Clinical segmentation typically requires a high-quality image with relevant features and domain experts for the best results. Due to this, automatic segmentation is a necessity in modern society since gliomas are considered highly malignant. Encoder-decoder-based structures, as popular as they are, have some areas where the research is still in progress, like reducing the number of false positives and false negatives. Sometimes these models also struggled to capture the finest boundaries, producing jagged or inaccurate boundaries after segmentation. This research article introduces a novel and efficient method for segmenting out the tumorous region in brain images to overcome the research gap of the recent state-of-the-art deep learning-based segmentation approaches. The proposed 4-staged 2D-VNET + + is an efficient deep learning tumor segmentation network that introduces a context-boosting framework and a custom loss function to accomplish the task. The results show that the proposed model gives a Dice score of 99.287, Jaccard similarity index of 99.642 and a Tversky index of 99.743, all of which outperform the recent state-of-the-art techniques like 2D-VNet, Attention ResUNet with Guided Decoder (ARU-GD), MultiResUNet, 2D UNet, Link Net, TransUNet and 3D-UNet.

Indexed as

Brain NeoplasmsDeep LearningGliomaImage Processing, Computer-AssistedAlgorithmsBrainHumansMagnetic Resonance ImagingNeural Networks, ComputerBrain imagesContext boosting frameworkDeep learningGliomasImage segmentation

Identifiers

PMID41057637
PMCPMC12504681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.