Evidence map›Paper›PMID 41057513›Full record

ArticleScientific reports2025

Multi-modal deep learning framework for early detection of Parkinson's disease using neurological and physiological data for high-fidelity diagnosis.

Ayan Sar, Pranav Singh Puri, Huma Naz, Sumit Aich, Tanupriya Choudhury, Lubna Abdelkhreim Gabralla

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayan Sar *School of Computer Science, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, 248007, India.
Pranav Singh Puri *School of Computer Science, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, 248007, India.
Huma Naz *School of Computing, DIT University, Dehradun, India.
Sumit Aich *School of Computer Science, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, 248007, India.
Tanupriya Choudhury *School of Computer Science, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, 248007, India. tanupriya@ddn.upes.ac.in.
Lubna Abdelkhreim Gabralla *Department of Computer Science, Applied College, Princess Nourah bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.

Funding

Princess Nourah Bint Abdulrahman University PNURSP2025R178
6 · The paper itself

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative disorder that remained challenging for proper diagnosis in its early stages due to its heterogeneous symptom presentation and overlapping clinical features. Consequently, there is no consensus on effectively detecting early-stage PD and classifying motor symptom severity. Therefore, the proposed research introduced MultiParkNet, an avant-grade multi-modal deep learning framework for early-stage PD detection synthesizing diverse neurological and physiological data sources. The proposed system integrated audio speech patterns, motor skills drawing characteristics, neuroimaging data, and cardiovascular signals with different neural architectures for robust feature extraction and fusion. The probabilistic classification approach enhanced disease identification with high fidelity and early detection. The model demonstrated exceptional performance, with an average training accuracy of 99.67%, validation accuracy of 98.15% [Formula: see text] and test accuracy of 96.74% [Formula: see text] across cross-validation experiments. This novel architecture significantly improved diagnostic precision with a transformative, AI-driven approach for Parkinson's disease assessment and potential clinical implications.

Indexed as

Deep LearningParkinson DiseaseEarly DiagnosisFemaleHumansMaleNeural Networks, ComputerNeuroimagingDeep LearningEarly DiagnosisMulti-Modal FusionNeurodegenerative DiseaseParkinson’s Detection

Identifiers

PMID41057513
PMCPMC12504576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.