Evidence map›Paper›PMID 41057405›Full record

ArticleScientific reports2025

Perinatal vitamin A excess impacts vitamin A and lipid metabolism in rat offspring.

Angélique Berthomé, Tiffany Antoine, Laure Meiller, Roland Govers, Philippe Guichard, Charlotte Sabran, Teresa Gonzalez, Marion Nowicki, Claire Bordat, Patrick Borel and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Angélique Berthomé *Aix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Tiffany Antoine *Aix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Laure MeillerCentre de Recherche en Nutrition Humaine Rhône-Alpes, Laboratoire CarMeN, INSERM, INRAE, Université Claude Bernard Lyon 1, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, F-69310, France.
Roland GoversAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Philippe GuichardAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Charlotte SabranAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Teresa GonzalezAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Marion NowickiAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Claire BordatAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Patrick BorelAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Michel GrinoAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France.
Valérie SauvinetCentre de Recherche en Nutrition Humaine Rhône-Alpes, Laboratoire CarMeN, INSERM, INRAE, Université Claude Bernard Lyon 1, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, F-69310, France.
Emmanuelle ReboulAix-Marseille Univ, INRAE, INSERM, C2VN, Marseille, France. Emmanuelle.Reboul@inrae.fr.

Funding

CTCPA, Avignon, France PhD fellowship 2018CTCPA, Avignon, France PhD fellowship 2023Groupe Lipides et Nutrition Prix 2017Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement ANSSD 2016Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement PhD fellowship 2018Région Sud PhD fellowship 2023
6 · The paper itself

Abstract

Vitamin A (VA) supplementation has been recommended for pregnant women at-risk of deficiency, and is widely applied to children under 5 in developing countries. We addressed the effect of excessive VA exposure during pregnancy, lactation and first weeks of life on VA, vitamin E and lipid metabolism in rat offspring. Sprague-Dawley female rats were fed either a 2300 IU.kg

Indexed as

Lipid MetabolismPrenatal Exposure Delayed EffectsVitamin AAnimalsDietary SupplementsFemaleLactationLiverMalePregnancyRatsRats, Sprague-DawleyVitamin EVitamin AVitamin E[1-13C]oleateBioavailabilityIntestine, liverRetinolRetinyl estersVitamin A

Identifiers

PMID41057405
PMCPMC12504743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.