Evidence map›Paper›PMID 41057363›Full record

ArticleNature communications2025

Ecdysone signaling-induced dumpless1 expression controls nurse cell dumping in Drosophila oogenesis.

Jingshan Li, Zishan Pan, Xiaoqi Peng, Yu Feng, Junfeng Wu, Feiying Liang, Qili Feng, XiaoQiang Yu, Huimin Deng

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jingshan LiGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.ORCID http://orcid.org/0009-0000-1880-1752
Zishan PanGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.ORCID http://orcid.org/0009-0007-9620-0793
Xiaoqi PengGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.ORCID http://orcid.org/0009-0002-2133-8089
Yu FengGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.ORCID http://orcid.org/0009-0006-5893-9012
Junfeng WuGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.ORCID http://orcid.org/0009-0003-2957-5043
Feiying LiangGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.ORCID http://orcid.org/0009-0007-8642-0506
Qili FengGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China. qlfeng@scnu.edu.cn.ORCID http://orcid.org/0000-0003-2105-6831
XiaoQiang YuGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China. xqyu@m.scnu.edu.cn.ORCID http://orcid.org/0000-0003-1419-9009
Huimin DengGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China. denghuiminmin@163.com.ORCID http://orcid.org/0000-0002-6228-5764

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32170494
6 · The paper itself

Abstract

Nurse cell (NC) dumping, a process essential for oocyte development, involves the rapid cytoplasmic transfer from germline-derived NCs into the oocyte. However, its regulatory mechanism remains unclear. Here, we report that ecdysone signaling in stretch follicle cells (SFCs) regulates NC dumping through dumpless1, a ZAD-C

Indexed as

Drosophila melanogasterDrosophila ProteinsEcdysoneOogenesisAnimalsCRISPR-Cas SystemsFemaleIntegrin beta ChainsOocytesOvarian Folliclerho GTP-Binding ProteinsSignal TransductionTranscription FactorsDrosophila ProteinsEcdysoneIntegrin beta ChainsRho1 protein, Drosophilarho GTP-Binding ProteinsTranscription Factors

Identifiers

PMID41057363
PMCPMC12504741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.