Evidence map›Paper›PMID 41057301›Full record

ArticleNature communications2025

Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer.

Raaj Kishore Biswas, Matthew N Ahmadi, Adrian Bauman, Karen Milton, Nicholas A Koemel, Emmanuel Stamatakis

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Intensity-specific physical activity and mortality in 147,414 adults: a pooled accelerometer analysis.The international journal of behavioral nutrition and physical activity · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Raaj Kishore BiswasMackenzie Wearables Research Hub, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0003-4294-6323
Matthew N AhmadiMackenzie Wearables Research Hub, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-3115-338X
Adrian BaumanSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Karen MiltonNorwich Medical School, University of East Anglia, Norwich, UK.
Nicholas A KoemelMackenzie Wearables Research Hub, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-5463-6894
Emmanuel StamatakisMackenzie Wearables Research Hub, Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia. emmanuel.stamatakis@sydney.edu.au.ORCID http://orcid.org/0000-0001-7323-3225

Funding

Department of Health | National Health and Medical Research Council (NHMRC) APP 1194510
6 · The paper itself

Abstract

Current conventions, partly derived from self-reported data, typically equate 1 minute of vigorous physical activity (VPA) to 2 minutes of moderate physical activity (MPA). Using accelerometer-derived intensity classification in 73,485 UK Biobank participants (mean follow-up: 8.0 [1.0] years), we assess the equivalence of light activity (LPA) and MPA to 1 minute of VPA for all-cause (ACM) and cardiovascular (CVD) mortality, major adverse cardiovascular events (MACE), type 2 diabetes, and cancer outcomes. For a standardised 5%-35% risk reduction, the median MPA equivalent per minute of VPA is 4.1 (ACM, 95% CI: 4.1-4.2), 7.8 (CVD mortality, 7.7-8.0), 5.4 (MACE, 5.3-5.5), 9.4 (type 2 diabetes, 9.3-9.6), and 3.5 (cancer mortality, 3.4-3.5) minutes. For non-cancer outcomes, the median LPA equivalent per 1 minute of VPA ranges from 53 (ACM) to 94 minutes (type 2 diabetes), reflecting generally weaker dose-response curves of LPA with all outcomes. These findings indicate a substantial departure from self-reported estimates and support integrating device-based equivalence into guidelines and wearables.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2ExerciseNeoplasmsWearable Electronic DevicesAccelerometryAdultAgedFemaleHumansMaleMiddle AgedUnited Kingdom

Identifiers

PMID41057301
PMCPMC12504536

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.