Evidence map›Paper›PMID 41057247›Full record

ArticleOccupational and environmental medicine2025

Occupational exposures to inorganic dust are associated with emphysema: the SCAPIS cohort.

Mathias Holm, Linus Schioler, Anna Dahlman-Hoglund, Håkan Tinnerberg, Martin Andersson, Annelie Behndig, Anders Blomberg, Kerstin Cederlund, Jonas Eriksson Ström, Christer Janson and 14 more

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Article in Occupational and environmental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Mathias HolmDepartment of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden mathias.holm@amm.gu.se.ORCID 0000-0002-9327-5139
Linus SchiolerDepartment of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-8395-9625
Anna Dahlman-HoglundDepartment of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Håkan TinnerbergDepartment of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Martin AnderssonDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Annelie BehndigDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Anders BlombergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Kerstin CederlundDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-8084-8260
Jonas Eriksson StrömDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID 0000-0002-3434-988X
Christer JansonDepartment of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-5093-6980
Åse JohnssonDepartment of Radiology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Eva LindbergDepartment of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
Anders LindénDivision for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Stefan LjunggrenOccupational and Environmental Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Andrei MalinovschiDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-4098-7765
Anna-Carin OlinDepartment of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ida PesonenDepartment of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0001-8977-7462
Magnus SköldDepartment of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.
Magnus SvartengrenDepartment of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
Hanan TanashDepartment of Respiratory Medicine, Skånes universitetssjukhus Malmö, Lund University, Malmö, Sweden.
Per WollmerDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Xi-Ming YuanOccupational and Environmental Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Suneela ZaighamDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Kjell TorénDepartment of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-8509-7603

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere is a lack of knowledge about whether occupational exposures increase the risk of emphysema, especially in never-smokers. Our objective was to determine if occupational exposures are associated with emphysema and impaired diffusing capacity.

methodsIn the Swedish CArdioPulmonary bioImage Study (SCAPIS), persons from the general population aged 50-64 answered a questionnaire and underwent CT of the lung as well as assessment of the diffusing capacity of their lungs for carbon monoxide (DL

resultsIn this cross-sectional study (27 370 persons including 13 981 never-smokers), occupational exposure to inorganic dust was associated with emphysema (OR 1.25, 95% CI 1.07 to 1.47), also among never-smokers, (OR 1.46, 95% CI 1.00 to 2.11). There were associations with DL

conclusionsOccupational exposures to inorganic dust are associated with emphysema. The association is stronger in those with the combination of emphysema and impaired DL

Indexed as

Air Pollutants, OccupationalDustOccupational DiseasesOccupational ExposurePulmonary EmphysemaCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPulmonary Diffusing CapacitySurveys and QuestionnairesSwedenTomography, X-Ray ComputedAir Pollutants, OccupationalDustDustEpidemiologyOccupational Health

Identifiers

PMID41057247
PMCPMC12703276

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