Evidence map›Paper›PMID 41057181›Full record

ArticleBMJ open2025

Continuous physiological monitoring for the detection of postoperative deterioration: a protocol for a multistage, multicentre, international, prospective cohort study.

Afra Jiwa, Malcolm M Cameron, Adesoji O Ademuyiwa, Adewale Adisa, Maria Lorena Aguilera Arévalo, Michael Bahrami Hessari, Aneel Bhangu, Paul M Brennan, Neil Clark, Kathrin Cresswell and 19 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06565559 (EMUs), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06565559 recruitingnot on this map

EMUs: Enhanced Monitoring Using Sensors After Surgery

TypeobservationalSponsorUniversity of EdinburghRan2024 to 2027Enrolled1,332ConditionsSurgery, InpatientsArmsWearable Wireless Sensor
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Afra JiwaCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-6488-0698
Malcolm M CameronCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Adesoji O AdemuyiwaUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Adewale AdisaUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Maria Lorena Aguilera ArévaloUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Michael Bahrami HessariUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Aneel BhanguUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Paul M BrennanTranslational Neurosurgery, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-7347-830X
Neil ClarkCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Kathrin CresswellUsher Institute, University of Edinburgh, Edinburgh, UK.
Iwona CzerwinskaCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Luciana D'AdderioCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Eilidh GunnCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Parvez David HaqueUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Theresa IkegwuonuCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Ismail LawaniUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Dion MortonUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Audrey NganwaUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Faustin NtirenganyaUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Riinu PiusCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Antonio Ramos de la MedinaUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Sangeetha SamuelUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Catherine A ShawCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Stephen TabiriUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Rosie C TownsendUsher Institute, University of Edinburgh, Edinburgh, UK.
Chris VargheseDepartment of Surgery, The University of Auckland, Auckland, New Zealand.ORCID http://orcid.org/0000-0001-7369-8639
Dhruva GhoshUniversities of Birmingham and Edinburgh NIHR Global Health Research Unit on Global Surgery, Birmingham, UK.
Ewen M HarrisonCentre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK ewen.harrison@ed.ac.uk.
NIHR Global Health Research Unit on Global Surgery

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionIntermittent physiological monitoring and early warning scores (EWS) are limited in their ability to detect deteriorating patients in a timely manner. Wearable physiological sensors allow continuous remote monitoring and may be more timely and accurate in the identification of those at risk, compared with manual collection. This study aims to determine if wearable physiological sensors can be used for the early detection of postoperative deterioration, while being acceptable to patients and healthcare staff. METHODS AND ANALYSIS: This is a prospective observational cohort study that will recruit adults undergoing major surgery in Benin, India, Ghana, Guatemala, Mexico, Nigeria, Rwanda and the UK. Participants will wear wearable physiological chest and limb sensors before, during and after surgery for up to 10 days or until discharge. In this 'shadow-mode' study, continuous physiological observations collected using the devices will not be made available to clinical teams. No changes in participant care will result. Standard of care clinical data will be collected contemporaneously. Continuous sensor data will be used to design algorithms to predict deterioration and specific complications in this population. Usability and feasibility testing, through focus groups, interviews and questionnaires, will be undertaken with healthcare professionals and people undergoing surgery. ETHICS AND DISSEMINATION: Our stakeholder panel are directly involved in all aspects of this study, which will be conducted in accordance with the principles of the International Conference on Harmonisation Tripartite Guideline for Good Clinical Practice (ICH GCP) in addition to the principles of the ethics committee(s)/Institutional Review Boards (IRBs) who have reviewed and approved this study. Artificial intelligence (AI) prediction models will be reported in accordance with the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis+Artificial Intelligence (TRIPOD+AI) and Developmental and Exploratory Clinical Investigations of DEcision support systems driven by Artificial Intelligence (DECIDE-AI) reporting guidelines frameworks. TRIAL REGISTRATION NUMBER: NCT06565559.

Indexed as

Clinical DeteriorationPostoperative ComplicationsWearable Electronic DevicesAdultEarly Warning ScoreHumansMonitoring, PhysiologicMulticenter Studies as TopicProspective StudiesClinical Decision-MakingDigital TechnologyHealth informaticsSURGERYWearable Electronic Devices

Identifiers

PMID41057181
PMCPMC12506120

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.