Evidence map›Paper›PMID 41057147›Full record

ArticleStatistics in medicine2025

Sensitivity Analyses for Missing in Repeatedly Measured Outcome Data.

James F Troendle, Aparajita Sur, Eric S Leifer, Tiffany Powell-Wiley

Registry-linked trialAbstract read
In one paragraph

Article in Statistics in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03288207 (Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03288207 narecruitingnot on this map

Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Physical Activity Intervention

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2018 to 2027Enrolled325ConditionsObesityArmsStep it Up mobile app, Global Positioning System (GPS) Device, Bluetooth-enabled scale, Bluetooth-enabled glucometer, MRI: Image Reconstruction and Analysis Software (Device Manufacturer: NIH)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James F TroendleOffice of Biostatistics Research, Division of Intramural Research of the National Heart, Lung, and Blood Institute, NIH/DHHS, Bethesda, Maryland, USA.
Aparajita SurDepartment of Biostatistics, University of Minnesota, Minneapolis, Minnesota, USA.
Eric S LeiferOffice of Biostatistics Research, Division of Intramural Research of the National Heart, Lung, and Blood Institute, NIH/DHHS, Bethesda, Maryland, USA.
Tiffany Powell-WileySocial Determinants of Obesity and Cardiovascular Risk Laboratory, Division of Intramural Research of the National Heart, Lung, and Blood Institute, NIH/DHHS, Bethesda, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We discuss practical aspects of conducting sensitivity analyses for missing data with a repeatedly measured outcome. Our motivation is a SMART trial with a repeatedly measured outcome subject to missingness. We discuss and describe delta-based controlled imputation approaches to conducting sensitivity analyses for such trials that typically use linear mixed models for their primary analysis. We find that delta-based sensitivity analyses for trials with repeatedly measured outcome variables are enhanced by using MICE for the imputation. Further, including last-observed-before-time covariates is critical for a repeatedly observed outcome. We also develop some novel metrics for judging the adequacy of sensitivity analyses. Trial Registration: Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments: NCT03288207.

Indexed as

Clinical Trials as TopicData Interpretation, StatisticalHumansLinear ModelsModels, Statisticaldelta‐based controlled imputationlinear mixed modelmultiple imputation

Identifiers

PMID41057147
PMCPMC12503996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.