Evidence map›Paper›PMID 41056475›Full record

ArticleACS infectious diseases2025

Benzodeazaoxaflavin Sirtuin Inhibitors Inhibit

Roberto Gimmelli, Giuliana Papoff, Emanuele Fabbrizi, Michela Guida, Cristiana Lalli, Fulvio Saccoccia, Cécile Häberli, Jennifer Keiser, Daria Monaldi, Manfred Jung and 4 more

Abstract read
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Roberto GimmelliInstitute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome 00015, Italy.
Giuliana PapoffInstitute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome 00015, Italy.
Emanuele FabbriziDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome 00185, Italy.
Michela GuidaDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome 00185, Italy.ORCID 0000-0001-6487-1495
Cristiana LalliInstitute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome 00015, Italy.
Fulvio SaccocciaInstitute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome 00015, Italy.
Cécile HäberliSwiss Tropical and Public Health Institute, Allschwil 4002, Switzerland.
Jennifer KeiserSwiss Tropical and Public Health Institute, Allschwil 4002, Switzerland.
Daria MonaldiInstitute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Freiburg 79104, Germany.
Manfred JungInstitute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Freiburg 79104, Germany.ORCID 0000-0002-6361-7716
Christophe RomierDépartement de Biologie Structurale Intégrative, Université de Strasbourg, CNRS, INSERM, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch Cedex 67404, France.ORCID 0000-0002-3680-935X
Dante RotiliDepartment of Science, Roma Tre University, Viale Guglielmo Marconi 446, Rome 00146, Italy.ORCID 0000-0002-8428-8763
Antonello MaiDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome 00185, Italy.ORCID 0000-0001-9176-2382
Giovina RubertiInstitute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Adriano Buzzati-Traverso Campus, Monterotondo, Rome 00015, Italy.ORCID 0000-0003-2367-9709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schistosomiasis, a neglected tropical disease caused by trematodes of

Indexed as

Schistosoma mansoniSirtuin 2AnimalsHumansMiceSirtuin 2phenotypic and biochemical characterizationSchistosoma mansonisirtuinsSmSirt2 inhibitors

Identifiers

PMID41056475
PMCPMC12624727

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.